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Table 2 Percent antibiotic susceptibility of E. coli, and Klebsiella spp. during 2015/2016 compared to corresponding susceptibility results in 2011/2013a

From: A compilation of antimicrobial susceptibility data from a network of 13 Lebanese hospitals reflecting the national situation during 2015–2016

Antibiotic E. coli Klebsiella spp
2011/2013 N (%S) 2015/2016 N (%S) OR (95%CI) P 2011/2013 N (%S) 2015/2016 N (%S) OR (95% CI) P
Amikacin 29,667 (97%) 41,818 (90%) 0.29 (0.26–0.3) 0.0001 7768 (96%) 9498 (94%) 0.65 (0.57–0.75) 0.0001
Amoxicillin/clavulanic acid 30,411 (61%) 39,116 (59%) 1.13 (1.10–1.17) 0.0001 7883 (67%) 9069 (62%) 0.80 (0.75–0.86) 0.0001
Ampicillin 22,985 (23%) 35,906 (24%) 1.06 (1.02–1.10) 0.01
Aztreonam 27,221 (66%) 40,029 (57%) 0.65 (0.63–0.67) 0.0001 7020 (69%) 7924 (65%) 0.83 (0.78–0.90) 0.0001
Cefepime 26,314 (74%) 40,524 (62%) 0.60 (0.58–0.62) 0.0001
Cefoxitin 23,858 (87%) 33,104 (76%) 0.47 (0.45–0.50) 0.0001 5853 (89%) 6373 (83%) 0.60 (0.54–0.67) 0.0001
Ceftazidime 28,730 (71%) 41,816 (62%) 0.73 (0.71–0.76) 0.0001 7335 (71%) 9498 (64%) 0.73 (0.68–0.78) 0.0001
Ceftriaxone 20,059 (64%) 41,816 (58%) 0.85 (0.82–0.88) 0.0001 4750 (65%) 9498 (63%) 0.92 (0.85–0.99) 0.02
Cefuroxime 24,662 (59%) 33,106 (56%) 0.96 (0.93–0.99) 0.02 6516 (64%) 6579 (61%) 0.88 (0.82–0.94) 0.0004
Ciprofloxacin 29,411 (55%) 40,524 (57%) 1.22 (1.19–1.26) 0.0001 7883 (73%) 9311 (71%) 0.91 (0.85–0.97) 0.004
Gentamicin 29,327 (72%) 41,818 (72%) 1.00 (0.98–1.03) 1 7601 (75%) 9498 (78%) 1.18 (1.10–1.27) 0.0001
Imipenem 30,411 (99%) 41,813 (97%) 0.33 (0.29–0.37) 0.0001 7883 (98%) 9498 (96%) 0.49 (0.41–0.60) 0.0001
Nitrofurantoin 18,422 (96%) 29,434 (87%) 0.28 (0.26–0.30) 0.0001 4356 (52%) 5155 (59%) 1.33 (1.22–1.44) 0.0001
Piperacillin/tazobactam 28,739 (83%) 40,524 (76%) 0.84 (0.81–0.873) 0.0001 7618 (81%) 9292 (78%) 0.83 (0.77–0.90) 0.0001
Tigecycline 9716 (98%) 39,050 (96%) 0.24 (0.20–0.30) 0.0001 2243 (87%) 8546 (93%) 1.99 (1.71–2.31) 0.0001
Trimethoprim/sulfamethoxazole 29,689 (49%) 41,496 (53%) 1.13 (1.10–1.16) 0.0001 7709 (57%) 9498 (58%) 1.04 (0.98–1.11) 0.2
  1. KEY = CI confidence interval, N Number of isolates tested in each bacteria/antibiotic combination, OR Odds Ratio, S Susceptibility, % percent
  2. P < 0.05 is considered statistically significant
  3. aThe 2011/2013 data are taken from: Chamoun K, Farah M, Araj G, et al. Surveillance of antimicrobial resistance in Lebanese hospitals: retrospective nationwide compiled data. Int J Infect Dis. 2016;46:64–70