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Table 3 Accordance of the package sizes of selected drugs with guidelines for urinary tract infections I

From: Evaluation of accordance of antibiotics package size with recommended treatment duration of guidelines for sore throat and urinary tract infections

Drug Package size ISKRAa Min No. of packages Extra units IDSAb
Co-amoxiclav 10x1000 mg 2x1000 mg, 7 days 2 6 n/a
2x1000 mg, 10-14 days 2 (10 days) 0
2x1000 mg, 14 days 3 2
2x1000 mg, 28 days 6 4
12x1000mgc 2x1000 mg, 7 days 2 10
2x1000 mg, 10-14 days 2 (12 days) 0
2x1000 mg, 14 days 3 8
2x1000 mg, 28 days 5 4
14x1000 mgc 2x1000 mg, 7 days 1 0
2x1000 mg, 10-14 days 2 (14 days) 0
2x1000 mg, 14 days 2 0
2x1000 mg, 28 days 4 0
16x1000 mg 2x1000 mg, 7 days 1 2
2x1000 mg, 10-14 days 2 (14 days) 4
2x1000 mg, 14 days 2 4
2x1000 mg, 28 days 4 8
20x1000 mg 2x1000 mg, 7 days 1 6
2x1000 mg, 10-14 days 1 (10 days) 0
2x1000 mg, 14 days 2 12
2x1000 mg, 28 days 3 4
21x1000 mg 2x1000 mg, 7 days 1 7
2x1000 mg, 10-14 days 1 (10 days) 1
2x1000 mg, 14 days 2 14
2x1000 mg, 28 days 3 7
24x1000 mg 2x1000 mg, 7 days 1 10
2x1000 mg, 10-14 days 1 (12 days) 0
2x1000 mg, 14 days 2 20
2x1000 mg, 28 days 3 16
30x1000 mg 2x1000 mg, 7 days 1 16
2x1000 mg, 10-14 days 1 (14 days) 2
2x1000 mg, 14 days 1 2
2x1000 mg, 28 days 2 4
Cephalexin 16x500 mgc 2x1000 mg, 7 days 2 4 n/a
16x1000 mgc 2x1000 mg, 7 days 1 2
Cefixime 5x400 mgc 1x400 mg, 10-14 days 2 (10 days) 0 n/a
1x400 mg, 14 days 3 1
1x400 mg, 28 days 6 2
10x400 mgc 1x400 mg, 10-14 days 1 (10 days) 0
1x400 mg, 14 days 2 6
1x400 mg, 28 days 3 2
Cefuroxime 10x125 mgc 2x500 mg, 10-14 days 8 (10 days) 0 n/a
2x500 mg, 14 days 12 8
2x500 mg, 28 days 23 6
10x250 mgc 2x500 mg, 10-14 days 4 (10 days) 0
2x500 mg, 14 days 6 4
2x500 mg, 28 days 12 8
8x500 mg 2x500 mg, 10-14 days 3 (12 days) 0
2x500 mg, 14 days 4 4
2x500 mg, 28 days 7 0
10x500 mgc 2x500 mg, 10-14 days 2 (10 days) 0
2x500 mg, 14 days 3 2
2x500 mg, 28 days 6 4
12x500 mg 2x500 mg, 10-14 days 2 (12 days) 0
2x500 mg, 14 days 3 8
2x500 mg, 28 days 5 4
14x500 mgc 2x500 mg, 10-14 days 2 (14 days) 0
2x500 mg, 14 days 2 0
2x500 mg, 28 days 4 0
15x500 mg 2x500 mg, 10-14 days 2 (14 days) 2
2x500 mg, 14 days 2 2
2x500 mg, 28 days 4 4
16x500 mgc 2x500 mg, 10-14 days 2 (14 days) 4
2x500 mg, 14 days 2 4
2x500 mg, 28 days 4 8
20x500 mg 2x500 mg, 10-14 days 1 (10 days) 0
2x500 mg, 14 days 2 12
2x500 mg, 28 days 3 4
24x500 mg 2x500 mg, 10-14 days 1 (12 days) 0
2x500 mg, 14 days 2 20
2x500 mg, 28 days 3 16
Norfloxacin 20x400 mgc 2x400 mg, 3 days 1 14 n/a
  1. Co-amoxiclav – amoxicillin and clavulanic acid; n/a – not applicable; extra units of drugs are presented with reference to the original formulation
  2. aThe Intersectoral Society for Antibiotic Resistance Control (ISKRA) guidelines on antimicrobial treatment and prophylaxis of urinary tract infections
  3. bInternational Clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases
  4. cincluded in Croatian national reimbursement lists on 1st August 2018