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Table 4 Accordance of the package sizes of selected drugs with guidelines for urinary tract infections II

From: Evaluation of accordance of antibiotics package size with recommended treatment duration of guidelines for sore throat and urinary tract infections

Drug Package size ISKRAa Min No. of packages Extra units IDSAb Min No. of packages Extra units
Ciprofloxacin 10x250 mgc 2x500 mg, 7-10 days 4 (10 days) 0 2x500 mg, 7 days 3 2
2x500 mg, 14 days 6 4
1000 mg, 7 days (extended release) n/a n/a
2x500 mg, 28 days 12 8
10x500 mgc 2x500 mg, 7-10 days 2 (10 days) 0 2x500 mg, 7 days 2 6
2x500 mg, 14 days 3 2
1000 mg, 7 days (extended release) n/a n/a
2x500 mg, 28 days 6 4
Fosfomycinum 1x2000 mgc n/a 1x3000 mg n/a n/a
2x2000 mg n/a 1x3000 mg n/a n/a
1x3000 mgc n/a 1x3000 mg 1 0
2x3000 mgc n/a 1x3000 mg 1 1
Levofloxacin 1x500 mg n/a 1x750 mg, 5 days 8 0.5
5x500 mg n/a 1x750 mg, 5 days 2 2.5
7x500 mg n/a 1x750 mg, 5 days 2 6.5
10x500 mgc n/a 1x750 mg, 5 days 1 2.5
14x500 mg n/a 1x750 mg, 5 days 1 6.5
Nitrofurantoin 30x50 mgc 2x100 mg, 7 days 1 2 2x100 mg, 5 days (monohydrate, macrocrystals) 1 10
Sulfametoxazole, trimethoprim 20x120 mgc 2x960 mg, 28 days 23 12 2x960 mg, 3 days 3 12
2x960 mg, 14 days 12 16
20x480 mgc 2x960 mg, 28 days 6 8 2x960 mg, 3 days 1 8
2x960 mg, 14 days 3 4
20x960 mgc 2x960 mg, 28 days 3 4 2x960 mg, 3 days 1 14
2x960 mg, 14 days 2 12
  1. n/a – not applicable; extra units of drugs are presented with reference to the original formulation
  2. aThe Intersectoral Society for Antibiotic Resistance Control (ISKRA) guidelines on antimicrobial treatment and prophylaxis of urinary tract infections
  3. bInternational Clinical Practice Guidelines for the Treatment of Acute Uncomplicated Cystitis and Pyelonephritis in Women: A 2010 Update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases
  4. cincluded in Croatian national reimbursement lists on 1st of August 2018