Table 4 Multivariate analysis of the risk factors of mortality due to carbapenemase-producing Enterobacteriaceae bloodstream infection
Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Unadjusted OR (95% CI) | P | Adjusted OR (95% CI) | P | |
Age | 1.01 (0.99–1.03) | 0.23 | – | – |
Pneumonia | 2.48 (1.14–5.40) | 0.02 | – | – |
UTI | 0.18 (0.03–0.83) | 0.02 | – | – |
Community-acquired infection | 0.93 (0.87–0.99) | 0.06 | – | – |
ICU admission | 3.65 (1.75–7.61) | 0.001 | – | – |
General operation | 1.93 (0.91–4.09) | 0.08 | – | – |
Mechanical ventilation | 3.38 (1.65–6.95) | 0.001 | – | – |
APACHE II score | 1.25 (1.16–1.35) | < 0.001 | 1.23 (1.13–1.34) | < 0.001 |
Antibiotics therapy for CPE infection | 0.27 (0.09–0.75) | 0.03 | 0.12 (0.03–0.57) | 0.007 |
Colistin based therapy | 1.29 (0.65–2.58) | 0.05 | – | – |
Combination therapy | 0.54 (0.24–1.25) | 0.15 | – | – |