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Table 3 Results of well diffusion and MIC test

From: Doxycycline-encapsulated solid lipid nanoparticles as promising tool against Brucella melitensis enclosed in macrophage: a pharmacodynamics study on J774A.1 cell line

Methods Antibacterial activity
Well Diffusion Zone of inhibition (mm) in three time (h) and three concentration(μg/ml)
Doxycycline (50-25-12.5 μg/ml) DOX-SLN (50-25-12.5 μg/ml) Free SLN (blank) (50-25-12.5 μg/ml)
24 h 48 h 72 h 24 h 48 h 72 h 24 h 48 h 72 h
35 30 22 35 30 22 35 30 22 21 19 15 26 24 20 31 30 22 0 0 0 0 0 0 0 0 0
MIC MIC value (μg/ml)
doxycycline Dox-SLN free SLN (blank)
24 h 24 h 48 h 72 h 24 h 48 h 72 h
0.5 25 12.5 6.25 - - -