Table 3 Tests for significance of differences across the study period in MDRO infection incidence density (MDRO), hand hygiene compliance, and alcohol-based hand rub usage (AHRU), respectively, within and across trial arms (hand hygiene compliance data are from [15] and reprinted with permission)
ASH-trial arm | Tailoring-trial arm | Comparison of trial arms | ||||||
|---|---|---|---|---|---|---|---|---|
a) MDRO | Difference | 95%-CI | p-value | Difference | 95%-CI | p-value | F | p-value |
2014 vs. 2013 | -0.086 i. per 1 k inpatient days | [-0.629; 0.456] | p = 0.730 | -0.260 i. per 1 k inpatient days | [-0.803; 0.282] | p = 0.310 | 0.255 | p = 0.625 |
2015 vs. 2014 | 0.064 i. per 1 k inpatient days | [-0.355; 0.483] | p = 0.739 | -0.237 i. per 1 k inpatient days | [-0.656; 0.182] | p = 0.236 | 1.285 | p = 0.283 |
2015 vs. 2013 | -0.022 i. per 1 k inpatient days | [-0.400; 0.356] | p = 0.899 | -0.497 i. per 1 k inpatient days | [-0.857; -0.119] | p = 0.015 | 3.927 | p = 0.076 |
b) Hand hygiene compliance | Difference | 95%-CI | p-value | Difference | 95%-CI | p-value | Chi 2 | p-value |
2014 vs. 2013 | +13% | [9.8; 16.1] | p < 0.001 | +10% | [6.3; 12.6] | p < 0.001 | 2.3 | p = 0.126 |
2015 vs. 2014 | -4% | [-7.7; -1.2] | p = 0.007 | +6% | [2.5; 9.3] | p = 0.001 | 18.5 | p < 0.001 |
2015 vs. 2013 | +9% | [5.1; 11.8] | p < 0.001 | +16% | [11.9; 18.9] | p < 0.001 | 7.9 | p = 0.005 |
c) AHRU | Difference | 95%-CI | p-value | Difference | 95%-CI | p-value | F | p-value |
2014 vs. 2013 | +20 ml per inpatient day | [-12.2; 51.4] | p = 0.199 | +3 ml per inpatient day | [-29.7; 34.0] | p = 0.883 | 0.8 | p = 0.407 |
2015 vs. 2014 | +6 ml per inpatient day | [-10.2; 23.7] | p = 0.397 | -2 ml per inpatient day | [-18.7; 15.2] | p = 0.827 | 0.6 | p = 0.452 |
2015 vs. 2013 | +26 ml per inpatient day | [-1.1; 53.8] | p = 0.058 | +1 ml per inpatient day | [-27.0; 27.9] | p = 0.972 | 2.2 | p = 0.168 |