Table 1 Epidemiological, clinical and biological characteristics of preterm infants infected/colonized by Staphylococcus capitis NRCS-A clone in Neonatal Intensive Care Unit (NICU) at Nîmes University Hospital from 2012 to 2017

Number of patients (n)

23

7

7

0

37

Number of patients admitted to the NICU

1255

747

100

416

2518

Incidence of S. capitis (‰)

1.04

0.55

3.95

0*

0.85

Male, n (%)

14 (60.9)

5 (71.4)

5 (71.4)

–

24 (64.9)

Gestational age, weeks (range)

27 (25–35)

28 (24–33)

27 (24–29)

–

27 (25–34)

Body weight, g (range)

919 (560–2500)

1175 (790–1985)

1095 (680–1400)

–

995(560–2500)

Intrauterine growth restriction, n (%)

7 (30.4)

1 (14.3)

0 (0)

–

8 (21.6)

Death, n (%)

4 (17.4)

0 (0)

2 (28.6)

0 (0)

6 (16.2)

Death due to S. capitis, n (%)

2 (8.7)

0 (0)

0 (0)

0 (0)

2 (5.4)

Infection S. aureus

1.7

1.6

1.7

1.7

1.7

Infection S. capitis, n (%)

9 (39.1)

1 (14.3)

2 (28.6)

–

12 (32.4)

Blood, n (%)

7 (78)

1 (100)

2 (100)

–

10 (83)

Catheter, n (%)

2 (22)

0 (0)

0 (0)

2 (17)

Cutaneous, n (%)

0 (0)

0 (0)

0 (0)

–

0

Colonisation S. capitis

14

6

5

–

Blood, n (%)

3 (26)

0 (0)

0 (0)

–

3 (12)

Catheter, n (%)

9 (60)

6 (100)

5 (100)

–

20 (80)

Cutaneous, n (%)

2 (14)

0 (0)

0 (0)

–

2 (8)

Number of patients which have received antibiotics treatment before infection, n (%)

16 (69.6)

4 (57.1)

5 (71.4)

–

25 (67.6)

Number of patients which have received vancomycin used before infection, n (%)

8 (34.8)

2 (28.6)

3 (42.9)

–

13 (35.1)

DDD/1000HD^a Vancomycin

25.4

25.5

29.1

27.0

27.4

DDD/1000HD Linezolid

12.1

9.3

14.0

11.7

11.4