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Table 2 Patient characteristics and outcome by adherence or non-adherence to guidelines

From: The association between adherence to national antibiotic guidelines and mortality, readmission and length of stay in hospital inpatients: results from a Norwegian multicentre, observational cohort study

  Non-adherence (N = 667) Adherence (N = 1089) P-value
Patient characteristics
 Indication for treatment
  LRTI 161 (24.1) 372 (34.2) < 0.001
  COPD with LRTI 124 (18.6) 230 (21.1)  
  Sepsis 111 (16.6) 180 (16.5)  
  SSTI 72 (10.8) 115 (10.6)  
  GI-infection 44 (6.6) 34 (3.1)  
  UTI 80 (12.0) 99 (9.1)  
  Other infections 75 (11.2) 59 (5.4)  
 Charlson Comorbidity Index
  CCI = 0 240 (36.0) 432 (39.7) 0.083
  CCI = 1 212 (31.8) 373 (34.3)  
  CCI = 2 119 (17.8) 141 (13.0)  
  CCI = 3 45 (6.8) 65 (6.0)  
  CCI = 4 24 (3.6) 33 (3.0)  
  CCI > 4 27 (4.1) 45 (4.1)  
 Age, mean (std.dev.) 67.3 (18.2) 67.4 (19.1) 0.885
 Age
  <=45 92 (13.8) 161 (14.8) 0.680
  46–65 156 (23.4) 240 (22.0)  
  66–85 320 (48.0) 508 (46.7)  
  >85 99 (14.8) 180 (16.5)  
 Admitted from institution 120 (18.0) 135 (12.4) 0.001
 Discharged to institution 182 (29.0) 258 (24.4) 0.090
 Sex
  Male 352 (52.8) 565 (51.9) 0.717
  Female 315 (47.2) 524 (48.1)  
 Outcome
  In-hospital mortality 38 (5.7) 32 (2.9) 0.004
  30-day mortality 75 (11.2) 67 (6.2) < 0.001
  30-day readmission (n = 623/1047) 140 (22.5) 206 (19.7) 0.173
  LOSa, mean (std.dev.) (n = 623/1047) 7.3 (4.4) 6.7 (4.1) 0.004
  1. aLOS = Length of stay. All analysis was performed using chi-square tests, except mean age and LOS which were analysed using two-sample t-test. P-values in boldface are statistically significant (<0.05)