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Table 6 Diagnostic performance of the CarbaSCORE to predict “the presence of bacteria requiring carbapenem treatment”

From: Derivation and validation of a simple score to predict the presence of bacteria requiring carbapenem treatment in ICU-acquired bloodstream infection and pneumonia: CarbaSCORE

CarbaSCORE threshold

Sensitivity [CI 95%]

Specificity [CI 95%]

PPV [CI 95%]

NPV [CI 95%]

3

0.96 [0.89–1.00]

0.37 [0.32–0.42]

0.12 [0.11–0.13]

0.99 [0.97–1.00]

5

0.96 [0.89–1.00]

0.38 [0.33–0.43]

0.12 [0.11–0.13]

0.99 [0.97–1.00]

6

0.96 [0.89–1.00]

0.39 [0.34–0.45]

0.12 [0.11–0.13]

0.99 [0.97–1.00]

7

0.81 [0.67–0.96]

0.69 [0.64–0.74]

0.19 [0.15–0.22]

0.98 [0.96–1.00]

8

0.78 [0.63–0.93]

0.70 [0.66–0.76]

0.19 [0.15–0.23]

0.97 [0.96–0.99]

9

0.48 [0.30–0.67]

0.91 [0.88–0.94]

0.32 [0.21–0.46]

0.96 [0.94–0.97]

11

0.44 [0.26–0.63]

0.92 [0.88–0.95]

0.32 [0.20–0.45]

0.95 [0.93–0.97]

13

0.22 [0.07–0.41]

0.97 [0.95–0.98]

0.38 [0.15–0.62]

0.93 [0.92–0.95]

  1. PPV Positive Predictive Value, NPV Negative Predictive Value, CI Confidence Interval