Epidemiology and risk factors of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci infections in Zhejiang China from 2015 to 2017

Table 1 Resistance rates (%) of E. faecalis (E.fa) and E. faecium (E.fm) to antimicrobial agents during 2015 to 2017

Antimicrobial agent	2015		2016		2017		P value
Antimicrobial agent	E.fa(n = 9109)	E.fm (n = 7106)	E.fa(n = 10,740)	E.fm(n = 9135)	E.fa (n = 11,860)	E.fm (n = 10,379)	E.fa	E.fm
Ampicillin	5.72	88.22	4.66	89.58	3.04	89.13	0.021	< 0.001
Nitrofurantoin	3.95	51.90	3.19	54.96	2.56	55.47	< 0.001	< 0.001
Gentamicin-High	7.32	34.15	18.06	41.57	41.67	41.67	< 0.001	< 0.001
Ciprofloxacin	22.54	89.13	23.14	90.47	22.05	90.32	0.009	0.147
Linezolid	3.17	1.15	2.97	1.00	2.73	0.67	0.002	0.168
Tetracycline	77.29	38.33	76.90	33.75	76.32	30.77	< 0.001	0.243
Tigecycline	0	0	0	0	0	0	/	/
Teicoplanin	0	0.51	0	0.45	0	0.16	/	< 0.001
Vancomycin	0.67	1.69	0.37	1.22	0.42	0.90	< 0.001	0.006
Levofloxacin	20.78	87.49	20.43	89.04	19.79	88.47	0.009	0.195