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Table 1 Definitions of categories for the assessment of mortality related to Verona Integron-encoded Metallo-β-lactamase positive Pseudomonas aeruginosa

From: Mortality related to Verona Integron-encoded Metallo-β-lactamase-positive Pseudomonas aeruginosa: assessment by a novel clinical tool

Definition Description
Definitely related A patient died due to sepsis, severe sepsis or septic shock and had a recent (< 10 days) blood culture with VIM-PA, without other pathogens in a blood culture.*
Probably related A patient died due to sepsis, without a recent positive blood culture (blood cultures were not taken or negative < 10 days of death), but with a nosocomial infection according to CDC definitions1 AND the strong suspicion of VIM-PA as the pathogen causing sepsis (cultures from sterile sites e.g.; ascites, abscess, bile, empyema are positive with VIM-PA).
OR
A patient died due to sepsis and had a positive blood culture with VIM-PA longer than 10 days before death but within one month of death, without another pathogen isolated in blood cultures.
Possibly related A patient died due to sepsis and there were cultures with VIM-PA in sterile specimens other than blood cultures within two months prior to death, with no other cultured possible causative pathogens.
OR
A patient died due to respiratory failure with VIM-PA in respiratory specimens.
Not related The patient did not die due to infection.
AND/OR
The patient was merely colonized with VIM-PA. Colonization was defined as the presence of positive cultures of non-sterile sites with VIM-PA without signs of infection.
Unknown Insufficient data were available in the medical records.
  1. Abbreviations: VIM-PA: Verona Integron-encoded Metallo-β-lactamase-positive Pseudomonas aeruginosa
  2. *Definitions of sepsis are described in Additional file 1
  3. 1 Centers for Disease Control and Prevention. CDC/NHSN surveillance definition of healthcare-associated infection and criteria for specific types of infections in the acute care setting 2016 [updated January 2016. Available from: https://www.cdc.gov/nhsn/PDFs/pscManual/17pscNosInfDef_current.pdf]