Table 2 Characteristics of included patients (n = 67)
Characteristic | Total | Definitely related | Probably related | Possibly related | Not related | Unknown |
|---|---|---|---|---|---|---|
No. of patients (%) | 67 (100) | 15 (22.4) | 2 (3.0) | 15 (22.4) | 34 (50.7) | 1 (1.5) |
Male gender (%) | 33 (49.3) | 10 (66.7) | 2 (100) | 7 (46.7%) | 13 (38.2%) | 1 (100) |
Mean age at time of first isolation of VIM-PA (range, SD) | 56.6 (18–82, 14.2) | 53.0 (20–71, 13.3) | 46.1 (40–52, 9.0) | 58.3 (34–82, 12.6) | 57.5 (18–80, 15.1) | 79.1 |
Mean age at time of death (range, SD) | 57.0 (18–82, 14.0) | 53.3 (20–71, 13.5) | 46.3 (40–53, 8.8) | 58.8 (37–82, 11.8) | 57.8 (18–81, 15.0) | 79.1 |
Median LOS before first VIM-PA culture, days, (range) | 23 (0–244) | 22 (1–244) | 85 (80–90) | 37 (4–126) | 22 (0–202) | 0 |
28-day mortality (%) | 36 (53.7) | 11 (73.3) | 0 (0) | 7 (46.7) | 17 (50.0) | 1 (100) |
1-year mortality (%) | 61 (91.0) | 14 (93.3) | 2 (100) | 14 (93.3) | 30 (88.2) | 1 (100) |
Location of first VIM-PA; ICU (%) | 49 (73.1) | 13 (86.7) | 0 (0) | 13 (86.7) | 23 (67.6) | 0 (0) |
Ward of acquisition; ICU (%) | 47 (70.1) | 13 (86.7) | 0 (0) | 12 (80.0) | 22 (64.7) | 0 (0) |
Location of death; ICU (%) | 43 (64.2) | 14 (93.3) | 1 (50.0) | 9 (60.0) | 19 (55.9) | 0 (0) |
Nosocomial acquisition | 67 (100) | 15 (100) | 2 (100) | 15 (100) | 34 (100) | 1 (100) |
Source of infection | ||||||
Pneumonia (%) | 15 (22.4) | 7 (46.7) | 1 (50.0) | 7 (46.7) | 0 (0) | 0 (0) |
Gastro-intestinal (%) | 11 (16.4) | 4 (26.7) | 1 (50.0) | 6 (40.0) | 0 (0) | 0 (0) |
Pneumonia and/or gastro-intestinal (%) | 2 (3.0) | 1 (6.7) | 0 (0) | 1 (6.7) | 0 (0) | 0 (0) |
Pneumonia and/or skin and soft tissue (%) | 2 (3.0) | 2 (13.3) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
Gastro-intestinal and/or cardiovascular system (%) | 1 (1.5) | 0 (0) | 0 (0) | 1 (6.7) | 0 (0) | 0 (0) |
Gastro-intestinal and/or skin and soft tissue (%) | 1 (1.5) | 1 (6.7) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
No infection or undetermined (%) | 35 (52.2) | 0 (0) | 0 (0) | 0 (0) | 34 (100) | 1 (100) |
Charlson comorbidity scorea | ||||||
Median Charlson score (range) | 3 (0–9)b | 2 (0–6)c | 0.5 (0–1) | 2 (0–5) | 4 (1–9)d | 4 |