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Table 2 Distribution of carbapenemase genes detected by the Xpert Carba-R assay and the recovered carbapenemase-producing organisms

From: Diagnostic performance of the Xpert Carba-R assay for active surveillance of rectal carbapenemase-producing organisms in intensive care unit patients

Carbapenemase genes (No. of positive results from the Carba-R assay)

Recovered strains from additional rectal culture

PCR confirmation of the CPO strains

No. of patients

No. of CPO strains

blaKPC (n = 10)

Klebsiella pneumoniae

KPC

CPE

5

5

Escherichia coli

KPC

CPE

2

2

Klebsiella pneumoniae

Escherichia coli

KPC

KPC

CPE

1

2

No growth

No growth

No CPO

1

0

Not available

NA

NA

1

0

blaKPC, blaIMP-1 (n = 1)

Escherichia coli

Citrobacter koseri

KPC

KPC

CPE

1

2

blaKPC, blaOXA-48 (n = 1)

Klebsiella pneumoniae

Pseudomonas aeruginosa

KPC

Negative

CPE

1

1

blaNDM (n = 4)

Escherichia coli

KPC

CPE

1

1

Klebsiella pneumoniae

NDM

CPE

1

1

Pseudomonas aeruginosa

Negative

No CPO

1

0

Klebsiella pneumoniae

Negative

No CPO

1

0

blaVIM (n = 1)

Klebsiella pneumoniae

Escherichia coli

KPC

Negative

CPE

1

1

blaIMP-1 (n = 13)

Pseudomonas aeruginosa

IMP-1

CP-NF

2

2

Acinetobacter baumannii

Negative

No CPO

4

0

Pseudomonas aeruginosa

Negative

No CPO

2

0

Pseudomonas aeruginosa

NA

NA

1

0

No growth

No growth

No CPO

4

0

  1. Abbreviations: CPO carbapenemase-producing organism, CPE carbapenemase-producing Enterobacteriaceae, CP-NF carbapenemase-producing glucose nonfermenting gram-negative bacilli, NA not available