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Table 2 Distribution of carbapenemase genes detected by the Xpert Carba-R assay and the recovered carbapenemase-producing organisms

From: Diagnostic performance of the Xpert Carba-R assay for active surveillance of rectal carbapenemase-producing organisms in intensive care unit patients

Carbapenemase genes (No. of positive results from the Carba-R assay)Recovered strains from additional rectal culturePCR confirmation of the CPO strainsNo. of patientsNo. of CPO strains
blaKPC (n = 10)Klebsiella pneumoniaeKPCCPE55
Escherichia coliKPCCPE22
Klebsiella pneumoniae
Escherichia coli
KPC
KPC
CPE12
No growthNo growthNo CPO10
Not availableNANA10
blaKPC, blaIMP-1 (n = 1)Escherichia coli
Citrobacter koseri
KPC
KPC
CPE12
blaKPC, blaOXA-48 (n = 1)Klebsiella pneumoniae
Pseudomonas aeruginosa
KPC
Negative
CPE11
blaNDM (n = 4)Escherichia coliKPCCPE11
Klebsiella pneumoniaeNDMCPE11
Pseudomonas aeruginosaNegativeNo CPO10
Klebsiella pneumoniaeNegativeNo CPO10
blaVIM (n = 1)Klebsiella pneumoniae
Escherichia coli
KPC
Negative
CPE11
blaIMP-1 (n = 13)Pseudomonas aeruginosaIMP-1CP-NF22
Acinetobacter baumanniiNegativeNo CPO40
Pseudomonas aeruginosaNegativeNo CPO20
Pseudomonas aeruginosaNANA10
No growthNo growthNo CPO40
  1. Abbreviations: CPO carbapenemase-producing organism, CPE carbapenemase-producing Enterobacteriaceae, CP-NF carbapenemase-producing glucose nonfermenting gram-negative bacilli, NA not available