Fig. 2

Relative abundance of the total resistome profile in each metagenome sample. a Relative abundance of antibiotic resistance genes (ARGs) compared with the overall metagenome for each sample. Each point represents a sample resistome (control, n = 31; EVC001-fed, n = 29). Box plots denote the interquartile range (IQR), with horizontal lines representing the 25th percentile, median, and 75th percentiles. The whiskers represent the lowest and highest values within 1.5 times the IQR from the first and third quartiles, respectively. The asterisks on the top indicate significant P-values (Mann-Whitney test). b Relative abundance of ARGs according to their taxonomic identification. The shade of color represents genera belonging to the same bacterial class. The asterisks on the top indicate significant P-values (Kruskal-Wallis test)