From: Early-life gut microbiome modulation reduces the abundance of antibiotic-resistant bacteria
 | 7005–11 | 7005–5 | 7005–9 | 7084–1 | 7084–4 | 7084–5 | 7122–1 | 7122–2 | 7122–9 | 7174–2 | 7174–4 | 7174–5 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
CARD ID | Name | Percentage identity (%) to CARD protein sequences (TBLASTN; E-value ≤0.001) | |||||||||||
ARO:3000216 | acrB | 97.6 | 97.3 | 97.8 | 84.1 | 84.3 | 83.1 | 97.9 | 96.6 | 97.8 | 96.9 | 95.7 | 98.0 |
ARO:3003844 | mfd | 97.5 | 96.8 | 97.0 | 80.5 | 80.5 | N/A | 97.4 | N/A | 97.3 | N/A | 95.9 | 96.4 |
ARO:3000491 | acrD | 97.1 | 97.2 | 95.2 | 79.3 | 79.4 | 78.2 | 97.4 | 96.4 | 97.4 | 97.2 | 97.3 | 97.4 |
ARO:3000793 | mdtB | 95.4 | 93.8 | N/A | 81.4 | 81.4 | N/A | 95.8 | 93.3 | 95.8 | 91.4 | N/A | 96.0 |
ARO:3000794 | mdtC | 93.5 | 90.4 | N/A | 80.8 | 80.7 | N/A | 93.2 | 91.5 | 93.1 | 85.3 | 88.4 | 93.4 |
ARO:3000502 | AcrF | 95.7 | 93.2 | 95.6 | N/A | N/A | N/A | 95.7 | 94.6 | 94.9 | 94.0 | 91.8 | 96.4 |
ARO:3000830 | cpxA | 97.5 | 95.3 | 96.9 | N/A | N/A | N/A | 96.6 | 95.2 | 97.2 | 96.2 | 97.0 | 97.5 |
ARO:3000024 | patA | 96.2 | 95.2 | 95.4 | 84.9 | 84.7 | N/A | 96.6 | 96.2 | 96.7 | 92.1 | 96.4 | 96.7 |
ARO:3003950 | msbA | 97.6 | 96.5 | 97.3 | N/A | N/A | N/A | 97.5 | N/A | 97.5 | 97.1 | 94.2 | 97.5 |
ARO:3000074 | emrB | 97.9 | 97.0 | 96.0 | 84.4 | 84.3 | 83.6 | 97.7 | 96.8 | 97.6 | N/A | 95.7 | 97.9 |
ARO:3002985 | arnA | 96.7 | 96.3 | 95.4 | N/A | N/A | N/A | 97.0 | 96.7 | 96.9 | N/A | 95.1 | 97.0 |
ARO:3000237 | TolC | 97.2 | 96.4 | 95.3 | N/A | N/A | N/A | 97.4 | 97.0 | 97.5 | 97.0 | 91.1 | 97.2 |
ARO:3000518 | CRP | 98.3 | 98.0 | 96.1 | 85.8 | 85.8 | N/A | 98.1 | 95.8 | 98.1 | 97.5 | 98.1 | 98.3 |
ARO:3004126 | LamB | 97.4 | 96.9 | 96.5 | 83.5 | 83.5 | 83.6 | 97.5 | 97.0 | 97.8 | 97.1 | 97.2 | 97.5 |
ARO:3004055 | CpxR | 98.1 | 97.3 | 98.6 | 84.0 | 83.7 | 83.2 | 98.3 | 96.9 | 98.3 | 97.6 | 97.4 | 98.1 |
ARO:3000792 | mdtA | 94.6 | 90.5 | N/A | 77.5 | 77.7 | N/A | 94.8 | 91.4 | 95.0 | 91.0 | N/A | 95.7 |
ARO:3002986 | bacA | 97.2 | 96.8 | 95.6 | 80.7 | 80.7 | 79.3 | 97.7 | 97.8 | 97.9 | 96.4 | 96.6 | 97.8 |
ARO:3003578 | PmrF | 97.1 | 96.7 | 96.7 | N/A | N/A | N/A | 97.0 | 96.8 | 97.3 | N/A | 95.8 | 97.2 |
ARO:3001215 | mdtL | 95.8 | 95.6 | 95.2 | N/A | N/A | N/A | 96.3 | 95.5 | 96.2 | 95.2 | 95.8 | 96.4 |
ARO:3000027 | emrA | 96.6 | 96.4 | 95.5 | N/A | N/A | N/A | 97.2 | 95.4 | 97.2 | 92.6 | 95.8 | 96.5 |
ARO:3001328 | MdfA | 95.5 | 94.7 | N/A | 78.1 | 78.4 | N/A | 95.5 | 94.3 | 95.9 | N/A | 94.6 | 95.7 |
ARO:3003843 | leuO | 97.4 | N/A | 95.3 | N/A | N/A | N/A | 97.5 | 97.4 | 97.6 | 96.8 | 96.9 | 97.0 |
ARO:3003952 | YojI | 96.2 | N/A | 96.0 | 82.6 | 82.9 | 78.4 | 96.0 | 95.6 | 96.4 | N/A | 95.5 | 95.7 |
ARO:3001329 | mdtG | 96.6 | 95.3 | 96.5 | N/A | N/A | N/A | 96.9 | 93.9 | 96.9 | N/A | 96.1 | 97.2 |
ARO:3000516 | emrR | 97.7 | 97.7 | 96.8 | 83.3 | N/A | N/A | 97.7 | 96.2 | 97.7 | 89.6 | 96.1 | 97.7 |
ARO:3000309 | emrD | 97.3 | 96.9 | 96.8 | N/A | N/A | N/A | 97.1 | 97.1 | 97.4 | 93.4 | 95.5 | 97.1 |
ARO:3000828 | baeR | 96.0 | 94.2 | N/A | N/A | N/A | N/A | 96.5 | 94.1 | 96.4 | 95.4 | 95.6 | 95.8 |
ARO:3004043 | acrA | 98.7 | 97.3 | 98.0 | 78.1 | 78.2 | N/A | 98.7 | 97.9 | 98.5 | 96.8 | 90.6 | 98.7 |
ARO:3003841 | kdpE | 95.4 | 94.9 | 94.2 | N/A | N/A | N/A | 95.8 | N/A | 95.8 | 93.9 | 95.8 | 96.0 |
ARO:3001216 | mdtH | 97.9 | 95.2 | 97.3 | N/A | N/A | N/A | 98.0 | 96.2 | 98.2 | N/A | N/A | 97.9 |
ARO:3003049 | rosB | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
ARO:3004108 | rob | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
ARO:3001327 | MdtK | 75.1 | 73.9 | 74.9 | N/A | N/A | N/A | 74.8 | N/A | 74.7 | 74.4 | 73.9 | 75.0 |
ARO:3000263 | marA | 96.1 | 96.1 | N/A | N/A | N/A | N/A | 96.4 | 95.1 | 96.6 | 96.4 | N/A | 97.4 |
ARO:3002818 | msrB | 98.1 | N/A | 98.3 | 89.3 | 90.4 | 82.5 | 97.1 | 96.2 | 96.6 | N/A | 96.6 | 98.3 |
ARO:3000676 | H-NS | 98.1 | 98.6 | 95.9 | 87.1 | 85.4 | 83.2 | 97.3 | 95.9 | 98.1 | N/A | 96.7 | 98.8 |
ARO:3003048 | rosA | N/A | N/A | N/A | 73.9 | 74.5 | 72.1 | N/A | N/A | N/A | N/A | N/A | N/A |
ARO:3000378 | MexB | 73.2 | 80 | 92.3 | 94.6 | 83.3 | 94.7 | 81.2 | 91.1 | 79.1 | 86.4 | 100 | 78.5 |
ARO:3000826 | sdiA | 77.4 | 63.7 | N/A | 100 | 81.1 | N/A | 82.1 | 85.7 | 63.1 | 57.9 | N/A | 84.2 |
ARO:3000829 | baeS | 96.2 | 58.15 | 45.0 | 92.72 | 70.83 | 45.7 | 97.0 | 53.9 | 97.6 | 67.8 | 93.5 | 95.2 |
N. of total CARD hits | 75 | 70 | 81 | 38 | 38 | 18 | 74 | 61 | 77 | 226 | 55 | 408 | |
Taxonomy | Escherichia coli | Escherichia coli | Escherichia coli | Raoultella planticola | Raoultella planticola | Raoultella planticola | Escherichia coli | Escherichia coli | Escherichia coli | Escherichia coli | Escherichia coli | Escherichia coli | |
Ref. Genome Size (Mb) | 4.8 | 4.8 | 4.8 | 5.8 | 5.8 | 5.8 | 4.8 | 4.8 | 4.8 | 4.8 | 4.8 | 4.8 | |
Coverage (based on reference) | 22.1x | 8.7x | 7.5x | 14.6x | 40x | 5.4x | 32.7x | 8.14x | 37.3x | 6x | 7x | 28.6x | |
Number of contigs | 5 | 53 | 46 | 3 | 1 | 92 | 3 | 57 | 3 | 80 | 66 | 3 | |
N50 (Mb) | 1.57 | 1.29 | 1.68 | 2.32 | 5.47 | 4.12 | 4.67 | 1.14 | 4.67 | 0.51 | 0.83 | 4.83 |