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Table 5 Studies describing hospital costs among patients with resistant and multi-drug resistant K. pneumoniae

From: Economic burden of antibiotic resistance in ESKAPE organisms: a systematic review

Author

Bacteria

Comparison

Description of cost

Median cost in 2015 USD

Mean cost in 2015 USD

Case

Control

Median cost

Case

Control

Increase

Ratio

P-value

Mean cost

Case

Control

Increase

Ratio

P-value

Thaden et al. [82]

K. pneumoniae

MDR

Non-MDR

Total hospital cost

Median (IQR)

46,934(12470–153,881)

11,183(5955–29,452)

35,751(6515–124,429)

4.20

0.0300

Mean (SD)

115,868(163881)

163,881(48116)

86,991(115765)

4.01

0.0300

Xu et al. [51]

K. pneumoniae

MDR

Non-MDR

Total hospital cost

      

Mean (SD)

5132(10165)

10,165(4603)

1954(5563)

1.61

0.0010

K. pneumoniae

MDR

non-MDR

Antibiotic cost

      

Mean (SD)

263(378)

378(361)

  

0.5900

Huang et al. [90]

K. pneumoniae

CRKP

CSKP

Total hospital cost

Median (range)

22,207(10938–41,559)

11,368(4730–24,634)

10,838(6208–16,925)

1.95

< 0.001

      

K. pneumoniae

CRKP

CSKP

Hospital cost after culture

Median (range)

8912(3248–20,173)

6677(2554–14,832)

2235(693–5341)

1.33

0.0030

      

K. pneumoniae

CRKP

CSKP

Antibitoic cost

Median (range)

2139(710–4926)

933(240–2468)

1206(470–2457)

2.29

< 0.001

      
  1. MDR multi-drug resistance, CRKP carbapenem resistace K. pneumoniae, CSEC carbapenem susceptible K. pneumoniae, IQR interquartile range, USD the United States Dollars, SD standard deviation