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Table 2 Characteristics of the 54 E. faecium isolates based on patient data and molecular results

From: Hospital outbreak caused by linezolid resistant Enterococcus faecium in Upper Austria

Case Province Hospital Ward Isolate Isolation year Source Phenotype LRE mechanism ST CT Cluster numbera Linezolid MIC (mg/L) Tedizolid MIC (mg/L)
1 UA 2 2 Ef-03 2013 Wound swab LREfm unknown 80 1873 2 32 4
2 UA 4 5 Ef-11 2014 Stool LREfm G2576U, A2598G 117 24 1 > 256 32
2 UA 4 6 Ef-22 2014 Blood culture LREfm unknown 117 24 1 32 4
3 UA 6 13 Ef-44 2016 Wound swab LREfm unknown 80 1873 2 64 2
4 UA 4 10 Ef-36 2015 Wound swab LREfm unknown 80 1873 2 128 4
6 UA 4 5 Ef-17 2014 Urine LREfm G2576U 117 24 1 32 8
6 UA 4 5 Ef-20 2014 Stool LREfm unknown 117 24 1 64 2
7 UA 4 5 Ef-15 2014 Urine LREfm unknown 117 24 1 16 4
8 UA 4 11 Ef-43 2016 Throat LREfm G2576U 117 24 1 32 2
9 UA 4 5 Ef-05 2014 Stool LREfm unknown 117 24 1 16 2
10 V 5 N/A Ef-24 2015 Stool LREfm unknown 203 20 5 16 2
10 V 5 N/A Ef-25 2015 Stool LREfm unknown 203 20 5 16 2
11 UA 4 5 Ef-40 2015 Stool LREfm unknown 117 24 1 32 2
12 UA 4 6 Ef-18 2014 Urine LREfm G2576U 117 24 1 32 2
13 UA 4 5 Ef-37 2015 Stool LREfm unknown 117 24 1 64 2
14 UA 4 6 13639 2015 Blood culture LSEfm unknown 117 24 1 n.d. n.d.
14 UA 4 6 Ef-31 2015 Stool LREfm unknown 117 24 1 32 2
15 UA 4 9 Ef-30 2014 Urine LREfm unknown 80 1873 2 64 4
16 UA 4 5 Ef-28 2014 Urine LREfm G2576U 117 24 1 64 8
17 UA 4 6 Ef-35 2015 Stool LREfm unknown 80 16 3 64 4
19 UA 4 7 Ef-26 2017 Urine LREfm G2576U 117 1875 not clustered 64 8
20 UA 4 6 Ef-23 2014 Stool LREfm G2576U, A2598G 117 1872 1 32 4
20 UA 4 6 Ef-27 2014 Stool LREfm G2576U 117 24 1 32 16
21 UA 6 12 Ef-42 2016 Catheter LREfm G2576U, A2598G 80 315 4 64 4
22 UA 2 1 Ef-02 2013 Wound swab LREfm G2576U 80 1873 2 128 16
23 UA 4 5 Ef-39 2015 Stool LREfm unknown 117 24 1 4 1
24 UA 4 6 Ef-29 2014 Stool LREfm unknown 117 24 1 8 2
25 UA 4 5 Ef-48 2017 Stool LREfm unknown 117 24 1 16 1
26 UA 4 5 Ef-46 2017 Stool LREfm unknown 117 24 1 32 1
27 UA 4 5 Ef-19 2014 Urine LREfm unknown 117 24 1 32 2
27 UA 4 5 Ef-21 2014 Stool LREfm unknown 80 1879 not clustered 4 1
28 UA 4 5 Ef-47 2017 Stool LREfm unknown 80 1876 not clustered 32 2
29 UA 4 6 14921 2016 Blood culture LSEfm unknown 80 16 3 n.d. n.d.
29 UA 4 5 Ef-32 2015 Stool LREfm unknown 80 16 3 64 2
29 UA 4 5 Ef-33 2015 Blood culture LREfm unknown 80 16 3 64 4
29 UA 4 5 Ef-41 2016 Stool LSEfm unknown 117 929 6 2 2
30 UA 4 5 Ef-13 2014 Stool LREfm unknown 117 1878 not clustered 16 2
30 UA 4 5 Ef-14 2014 Stool LREfm G2576U 117 24 1 8 2
30 UA 4 6 Ef-34 2015 Urine LREfm unknown 117 24 1 64 2
31 UA 4 5 Ef-07 2014 Urine LREfm unknown 117 24 1 16 2
31 UA 4 5 Ef-08 2014 Stool LREfm unknown 117 24 1 16 2
32 UA 4 5 Ef-12 2014 Stool LREfm unknown 117 24 1 16 2
33 UA 3 3 Ef-04 2013 Eye swab LREfm G2576U 80 1873 2 32 4
34 UA 6 16 Ef-38 2015 Blood culture LREfm unknown 80 315 4 32 2
35 UA 4 5 Ef-09 2014 Stool LREfm G2576U 117 24 1 16 2
36 C 1 1 Ef-01 2012 Wound swab LREfm unknown 192 1877 not clustered 16 2
37 UA 4 5 Ef-45 2016 Stool LREfm unknown 78 1874 not clustered 32 4
38 UA 6 15 14962 2016 Blood culture LSEfm n.a. 1479 not assigned not clustered n.d. n.d.
39 UA 4 5 12981 2014 Blood culture LSEfm n.a. 80 16 3 n.d. n.d.
40 C 7 14 Ef-51 2018 Urine LREfm G2576U 117 929 6 16 2
41 UA 6 15 14522 2015 Blood culture LSEfm n.a. 80 1873 2 n.d. n.d.
42 UA 4 4 15549 2016 Blood culture LSEfm n.a. 1466 not assigned not clustered n.d. n.d.
43 UA 4 7 15378 2016 Blood culture LSEfm n.a. 80 not assigned 4  n.d.  n.d.
45 UA 4 4 15925 2017 Blood culture LSEfm n.a. 80 467 not clustered n.d. n.d.
  1. aNumbering allocated for each cluster in the MST
  2. n.a. not applicable, n.d. not done
  3. C Carinthia, CT Cluster type (cgMLST), MST minimum spanning tree, ST Sequence Type (classical MLST), UA Upper Austria, V Vienna