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Table 5 Univariable analysis of antibiotic related variables by specialty

From: Antibiotic prescribing in general medical and surgical specialties: a prospective cohort study

  Medicine 162 n (%) Surgery 164 n (%) p value *
Total number of courses of antibiotics 395 461
Route of antibiotics (as a total of all courses)
 Intravenous 200 (51) 395 (86) < 0.001
 Oral 195(49) 66 (14)
Number of antibiotics during spell
 1 36 (22.22) 12 (7.32) 0.001
 2 52 (32.10) 68 (41.46)
 ≥ 3 74 (45.68) 84 (51.22)
Antibiotic exposure days
 1–3 days 65 (40) 56 (34) 0.134
 4–7 days 55 (34) 52 (32)
 7–14 days 28 (17) 33 (20)
 ≥ 15 14 (9) 23 (14)
Cumulative antibiotic days
 1–7 days 94 (58) 70 (43) 0.016
 8–14 days 46 (28) 44 (27)
 ≥ 15 22 (14) 50 (30)
Antibiotic rank
 Narrow 11(6.79) 6 (3.66) 0.507
 Broad 98 (60.49) 95 (57.93)
 Extended 47 (29.00) 56 (34.15)
 Restricted 6 (3.70) 7 (4.27)
Change to initial antibiotic course
 No change/discontinued 76 (46.91) 90 (54.88) 0.0037
 Antibiotic escalated 31 (19.14) 49 (29.88)
 Antibiotic de-escalated 55(33.95) 25 (15.24)
Antibiotic compliant to local policy
 Yes 131 (80.86) 108 (65.85) < 0.001
 No 30 (18.52) 35 (21.34)
 Unclear 1 (0.62) 21 (12.80)
Antibiotic compliant to local policy (‘unclear’ treated as missing)
 Yes 131 (81.37) 108 (75.52) 0.215
 No 30 (18.63) 35 (24.48)
Antibiotic prescribed on discharge
 Yes 80 (49) 73 (45) 0.677
 No 67 (41) 74 (45)
 No data/Patient died 15 (9) 17 (10)
  1. *P values calculated using Pearson Chi-Squared test or Fisher’s exact test