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Table 6 Multiple logistic regression examining the association between escalating antibiotic therapy and the selected variables, adjusting for specialty (n = 326)

From: Antibiotic prescribing in general medical and surgical specialties: a prospective cohort study

  OR 95% CI Crude P Adjusted ORa 95% CI Adjusted P value
Specialty
 Medicine 1    1   
 Surgery 1.801 1.076–3.013 0.024 1.942 1.067–3.534 0.030
Comorbidity score
 Low 1    1   
 Mod 1.164 0.629 – 0.629 0.845 0.402–1.773 0.655
 Severe 1.380 2.151
0.741–2.570
0.310 1.123 0.541–2.354 0.747
Culture and sensitivity
 Negative 1    1   
 Positive 0.569 0.236 – 0.209 0.583 0.218–1.559 0.282
 No culture 0.378 1.371
0.192–0.746
0.005 0.470 0.219–1.009 0.053
Los
 1–7 1    1   
 8–14 2.027 0.998 – 0.051 2.012 0.962–4.215 0.064
 ≥ 15 5.758 4.117
3.137–10.567
< 0.001 5.138 2.66–9.910 < 0.001
Sign of infection on chest X-ray
 No 1    1   
 Yes 1.145 0.563 – 0.709 1.405 0.635–3.109 0.402
 No chest X-ray 0.486 2.323
0.273–0.863
0.014 0.610 0.328–1.173 0.142
  1. a Adjusted for all other variables included within this table