Table 6 Multiple logistic regression examining the association between escalating antibiotic therapy and the selected variables, adjusting for specialty (n = 326)
From: Antibiotic prescribing in general medical and surgical specialties: a prospective cohort study
OR | 95% CI | Crude P | Adjusted ORa | 95% CI | Adjusted P value | |
|---|---|---|---|---|---|---|
Specialty | ||||||
Medicine | 1 | 1 | ||||
Surgery | 1.801 | 1.076–3.013 | 0.024 | 1.942 | 1.067–3.534 | 0.030 |
Comorbidity score | ||||||
Low | 1 | 1 | ||||
Mod | 1.164 | 0.629 – | 0.629 | 0.845 | 0.402–1.773 | 0.655 |
Severe | 1.380 | 2.151 0.741–2.570 | 0.310 | 1.123 | 0.541–2.354 | 0.747 |
Culture and sensitivity | ||||||
Negative | 1 | 1 | ||||
Positive | 0.569 | 0.236 – | 0.209 | 0.583 | 0.218–1.559 | 0.282 |
No culture | 0.378 | 1.371 0.192–0.746 | 0.005 | 0.470 | 0.219–1.009 | 0.053 |
Los | ||||||
1–7 | 1 | 1 | ||||
8–14 | 2.027 | 0.998 – | 0.051 | 2.012 | 0.962–4.215 | 0.064 |
≥ 15 | 5.758 | 4.117 3.137–10.567 | < 0.001 | 5.138 | 2.66–9.910 | < 0.001 |
Sign of infection on chest X-ray | ||||||
No | 1 | 1 | ||||
Yes | 1.145 | 0.563 – | 0.709 | 1.405 | 0.635–3.109 | 0.402 |
No chest X-ray | 0.486 | 2.323 0.273–0.863 | 0.014 | 0.610 | 0.328–1.173 | 0.142 |