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Table 4 Comparison of antibody and antigen detection rates in acute or chronic brucellosis

From: Detection of Brucellae in peripheral blood mononuclear cells for monitoring therapeutic efficacy of brucellosis infection

Phase

Therapy course

Reactivity (Nb/%)

Total

P value Intragroup

+

Acute

SAT

0

10 (100%)

0

10

0.467

1–2

31 (96.9%)

1 (3.1%)

32

≥3

26 (100%)

0

26

 

Overall

67 (98.5%)

1 (1.5%)

68

ELISA

0

9 (90%)

1 (10%)

10

0.209

 

1–2

30 (93.8%)

2 (6.2%)

32

 

≥3

26 (100%)

0

26

 

Overall

65 (95.6%)

3 (4.4%)

68

IFS

0

7 (70%)

3 (30%)

10

0.038*

1–2

27 (84.4%)

5 (15.6%)

32

≥3

14 (53.8%)

12 (46.2%)

26

  

Overall

48 (70.6%)

20 (29.4%)

68

Chronic

SAT

0

12 (92.3%)

1 (7.7%)

13

0.061

1–2

11 (73.3%)

4 (26.7%)

15

≥3

36 (62.1%)

22 (37.9%)

58

 

Overall

59 (68.6%)

27 (31.4%)

86

ELISA

0

13 (100%)

0

13

0.299

 

1–2

15 (100%)

0

15

 

≥3

55 (94.8%)

3 (5.2%)

58

 

Overall

83 (96.5%)

3 (3.5%)

86

IFS

0

9 (69.2%)

4 (30.8%)

13

0.988

1–2

10 (66.7%)

5 (33.3%)

15

≥3

39 (67.2%)

19 (32.8%)

58

  

Overall

58 (67.4%)

28 (32.6%)

86

  1. *A significant difference was found in IFS detection rate among therapy courses 0, 1–2 and ≥ 3 (P = 0.038), or between therapy courses 0–1-2 and ≥ 3 (P = 0.017) or 1–2 and ≥ 3 (P = 0.011) from acute phase of brucellosis patients