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Table 5 CCRT outcomes and antimicrobial adverse events by the fourth day of CCRT activation by group

From: Appropriateness of antimicrobial use among septic patients managed by the critical care response team: an opportunity for improvement through de-escalation

 Cases
N = 157
Control
N = 158
Total
N = 315
p-value
Outcome
 Stay at floor77 (49.0%)94 (59.5%)171 (54.3%)0.063
 Admission to intensive care unit69 (43.9%)45 (28.5%)114 (36.2%)0.004
 Death7 (4.5%)2 (1.3%)9 (2.9%)0.104
 Discharge home0 (0.0%)2 (1.3%)2 (0.6%)0.498
 Others0 (0.0%)2 (1.3%)2 (0.6%)0.498
Antimicrobial adverse events
 None107 (68.2%)115 (72.8%)222 (70.5%)0.270
 One36 (22.9%)36 (22.8%)72 (22.9%) 
 Two or more14 (8.9%)7 (4.4%)21 (6.7%) 
Types of antimicrobial adverse events
 Renal21 (13.4%)18 (11.4%)39 (12.4%)0.593
 Hematologic17 (10.8%)19 (12.0%)36 (11.4%)0.738
 Gastrointestinal17 (10.8%)7 (4.4%)24 (7.6%)0.032
 Hepatic8 (5.1%)6 (3.8%)14 (4.4%)0.576
 Skin3 (1.9%)1 (0.6%)4 (1.3%)0.371
 Anaphylaxis0 (0.0%)1 (0.6%)1 (0.3%)> 0.99