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Table 5 The association between the minimum inhibitory concentrations and blaOXA carbapenemase genes of 154 isolates that were resistant to imipenem and meropenem

From: Study of genetic diversity, biofilm formation, and detection of Carbapenemase, MBL, ESBL, and tetracycline resistance genes in multidrug-resistant Acinetobacter baumannii isolated from burn wound infections in Iran

Target genes

Number of isolates with minimal inhibitory concentration of imipenema and meropenemb

P-value

No. (%) of isolate

8 μg/ml

16 μg/ml

32 μg/ml

64 μg/ml

128 μg/ml

256 μg/ml

blaOXA-23-likea

2 (1.5)

28 (21.4)

41 (31.3)

32 (24.4)

15 (11.5)

13 (9.9)

0.1

131 (85.1)

blaOXA-40-likea

4 (4.8)

9 (10.7)

13 (15.5)

29 (34.5)

19 (22.6)

10 (11.9)

0.2

84 (54.5)

blaOXA-51-likea

10 (6.5)

32 (20.8)

42 (27.3)

35 (22.7)

22 (14.3)

13 (8.5)

0.1

154 (100)

blaOXA-23-like + blaOXA-40-likea

2 (2.8)

7 (10)

13 (18.6)

26 (37.2)

13 (18.6)

9 (12.8)

0.1

70 (45.5)

ISAba1 + blaOXA-23-likea

0 (0)

28 (21.7)

41 (31.8)

32 (24.8)

15 (11.6)

13 (10.1)

0.1

129 (83.8)

ISAba1 + blaOXA-51-likea

0 (0)

2 (4.8)

7 (16.7)

8 (19.1)

12 (28.6)

13 (30.9)

0.2

42 (27.3)

blaOXA-23-likeb

1 (0.8)

31 (23.7)

33 (25.2)

29 (22.1)

22 (16.8)

15 (11.4)

0.08

131 (85.1)

blaOXA-40-likeb

2 (2.4)

6 (7.2)

15 (17.8)

30 (35.7)

21 (25)

10 (11.9)

0.09

84 (54.5)

blaOXA-51-likeb

3 (1.9)

42 (27.3)

34 (22.1)

30 (19.5)

29 (18.8)

16 (10.4)

0.2

154 (100)

blaOXA-23-like + blaOXA-40-likeb

1 (1.4)

3 (4.3)

11 (15.7)

27 (38.6)

20 (28.6)

8 (11.4)

0.1

70 (45.5)

ISAba1 + blaOXA-23-likeb

0 (0)

30 (23.2)

33 (25.6)

29 (22.5)

22 (17.1)

15 (11.6)

0.08

129 (83.8)

ISAba1 + blaOXA-51-likeb

0 (0)

3 (7.2)

5 (11.9)

13 (30.9)

10 (23.8)

11 (26.2)

0.2

42 (27.3)

  1. Abbreviations: arelated to the concentration of imipenem; brelated to the concentration of meropenem