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Table 3 Comparing clinical characteristics between OHD patients and non-OHD patients from KP-PLA

From: Clinical, microbiological, and molecular epidemiological characteristics of Klebsiella pneumoniae-induced pyogenic liver abscess in southeastern China

Characteristic OHD patients (n = 29) non-OHD patients (n = 134) P Value
Age, years 67.0 (62.0-73.0) 61.0 (51.0-70.0) 0.053
Gender    0.451
 Male 16 (55.2) 84 (62.7)  
 Female 13 (44.8) 50 (37.3)  
Underlying or concomitant conditions    
 Diabetes mellitus 7 (24.1) 74 (55.2) 0.002*
 History of intra-abdominal trauma or surgery 26 (89.7) 20 (14.9) 0.000*
 Hypertension 5 (17.2) 45 (33.6) 0.084
 Malignancy 2 (6.9) 5 (3.7) 0.797
Admission temperature (°C) 38.0 (37.3-39.0) 39.0 (38.0-39.5) 0.019*
Clinical Symptoms
 Fever (>37.5°C) 20 (69.0) 117 (87.3) 0.030*
 Chill 23 (79.3) 109 (81.3) 0.800
 Abdominal pain 14 (48.3) 51 (38.1) 0.308
 Vomit 4 (13.8) 20 (14.9) 1.000
 Frail 3 (10.3) 22 (16.4) 0.590
 Abdominal distension 2 (6.9) 3 (2.2) 0.216
Invasive procedure 25 (86.2) 116 (86.6) 1.000
Use of hormones and/or immunosuppressants 11 (37.9) 41 (30.6) 0.442
Multiplicity of the abscess    0.409
 Single 19 (65.5) 98 (73.1)  
 Multiple (≥2 abscesses) 10 (34.5) 36 (26.9)  
Laboratory examination
 WBC count, ×109/L 8.9 (5.9-11.6) 11.1 (8.2-14.0) 0.014*
 RBC count, ×1012/L 3.9 (3.5-4.1) 3.9 (3.6-4.2) 0.667
 ALT(U/L) 33.0 (14.0-49.0) 43.0 (27.0-82.8) 0.033*
 AST(U/L) 35.0 (26.0-50.0) 37.0 (24.0-70.8) 0.621
 Albumin, g/L 29.8±5.0 29.3±5.1 0.609
Method of abscess treatment
 Simple antibacterial 6 (20.7) 24 (17.9) 0.726
 Abscess drainage 20 (69.0) 109 (81.3) 0.137
 Surgical removal 3 (10.3) 1 (0.7) 0.021*
Prognosis of abscess    0.233
 Effective 18 (62.1) 98 (73.1)  
 Ineffective 11 (37.9) 36 (26.9)  
Metastatic infections    1.000
 Endophthalmitis 0 (0.0) 1 (0.7)  
 Cephalomeningitis 0 (0.0) 1 (0.7)  
 Bacterial peritonitis 0 (0.0) 1 (0.7)  
 Pneumonia 0 (0.0) 1 (0.7)  
Clinical outcomes    
 Length of stay in hospital, days 23.0 (15.0-28.0) 16.0 (12.0-25.0) 0.045*
 Admission to ICU 1 (3.4) 15 (11.2) 0.354
 Septic shock 3 (10.3) 12 (9.0) 1.000
 Septicemia 5 (17.2) 15 (11.2) 0.557
 In-hospital deaths 0 (0.0) 1 (0.7) 1.000
  1. Values are presented as median (25th - 75th percentile), mean ± SD or No. (%) of patients
  2. WBC white blood cell, RBC red blood cell, ALT alanine aminotransferase, AST aspartate aminotransferase, ICU intensive care unit *P < 0.05