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Table 3 Comparing clinical characteristics between OHD patients and non-OHD patients from KP-PLA

From: Clinical, microbiological, and molecular epidemiological characteristics of Klebsiella pneumoniae-induced pyogenic liver abscess in southeastern China

Characteristic

OHD patients (n = 29)

non-OHD patients (n = 134)

P Value

Age, years

67.0 (62.0-73.0)

61.0 (51.0-70.0)

0.053

Gender

  

0.451

 Male

16 (55.2)

84 (62.7)

 

 Female

13 (44.8)

50 (37.3)

 

Underlying or concomitant conditions

   

 Diabetes mellitus

7 (24.1)

74 (55.2)

0.002*

 History of intra-abdominal trauma or surgery

26 (89.7)

20 (14.9)

0.000*

 Hypertension

5 (17.2)

45 (33.6)

0.084

 Malignancy

2 (6.9)

5 (3.7)

0.797

Admission temperature (°C)

38.0 (37.3-39.0)

39.0 (38.0-39.5)

0.019*

Clinical Symptoms

 Fever (>37.5°C)

20 (69.0)

117 (87.3)

0.030*

 Chill

23 (79.3)

109 (81.3)

0.800

 Abdominal pain

14 (48.3)

51 (38.1)

0.308

 Vomit

4 (13.8)

20 (14.9)

1.000

 Frail

3 (10.3)

22 (16.4)

0.590

 Abdominal distension

2 (6.9)

3 (2.2)

0.216

Invasive procedure

25 (86.2)

116 (86.6)

1.000

Use of hormones and/or immunosuppressants

11 (37.9)

41 (30.6)

0.442

Multiplicity of the abscess

  

0.409

 Single

19 (65.5)

98 (73.1)

 

 Multiple (≥2 abscesses)

10 (34.5)

36 (26.9)

 

Laboratory examination

 WBC count, ×109/L

8.9 (5.9-11.6)

11.1 (8.2-14.0)

0.014*

 RBC count, ×1012/L

3.9 (3.5-4.1)

3.9 (3.6-4.2)

0.667

 ALT(U/L)

33.0 (14.0-49.0)

43.0 (27.0-82.8)

0.033*

 AST(U/L)

35.0 (26.0-50.0)

37.0 (24.0-70.8)

0.621

 Albumin, g/L

29.8±5.0

29.3±5.1

0.609

Method of abscess treatment

 Simple antibacterial

6 (20.7)

24 (17.9)

0.726

 Abscess drainage

20 (69.0)

109 (81.3)

0.137

 Surgical removal

3 (10.3)

1 (0.7)

0.021*

Prognosis of abscess

  

0.233

 Effective

18 (62.1)

98 (73.1)

 

 Ineffective

11 (37.9)

36 (26.9)

 

Metastatic infections

  

1.000

 Endophthalmitis

0 (0.0)

1 (0.7)

 

 Cephalomeningitis

0 (0.0)

1 (0.7)

 

 Bacterial peritonitis

0 (0.0)

1 (0.7)

 

 Pneumonia

0 (0.0)

1 (0.7)

 

Clinical outcomes

   

 Length of stay in hospital, days

23.0 (15.0-28.0)

16.0 (12.0-25.0)

0.045*

 Admission to ICU

1 (3.4)

15 (11.2)

0.354

 Septic shock

3 (10.3)

12 (9.0)

1.000

 Septicemia

5 (17.2)

15 (11.2)

0.557

 In-hospital deaths

0 (0.0)

1 (0.7)

1.000

  1. Values are presented as median (25th - 75th percentile), mean ± SD or No. (%) of patients
  2. WBC white blood cell, RBC red blood cell, ALT alanine aminotransferase, AST aspartate aminotransferase, ICU intensive care unit *P < 0.05