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Table 4 Comparing microbiological and molecular-epidemiological characteristics of K. pneumoniae strains between OHD patients and non-OHD patients

From: Clinical, microbiological, and molecular epidemiological characteristics of Klebsiella pneumoniae-induced pyogenic liver abscess in southeastern China

Characteristic

Kp from OHD patients (n = 29)

Kp from non-OHD patients (n = 134)

P Value

Hypermucoviscosity

8 (27.6)

42 (31.3)

0.691

Capsular serotypes

 K1

11 (37.9)

55 (41.0)

0.757

 K2

5 (17.2)

26 (19.4)

0.788

 K5

1 (3.4)

7 (5.2)

1.000

 K20

1 (3.4)

2 (1.5)

0.447

 non-type

11 (37.9)

43 (32.1)

0.545

Virulence genes

 aerobactin

22 (75.9)

117 (87.3)

0.197

 rmpA

25 (86.2)

130 (97.0)

0.049*

 iroN

4 (13.8)

36 (26.9)

0.138

 kfuBC

17 (58.6)

99 (73.9)

0.100

 wcaG

18 (62.1)

94 (70.1)

0.395

 ybtA

23 (79.3)

97 (72.4)

0.443

 magA

9 (31.0)

65 (48.5)

0.087

 fimH

29 (100.0)

127 (94.8)

0.451

 mrkD

29 (100.0)

134 (100.0)

NA

 uge

26 (89.7)

121 (90.3)

1.000

 entB

24 (82.8)

120 (89.6)

0.475

 ureA

27 (93.1)

118 (88.1)

0.646

Antimicrobial resistance

 Ampicillin

29 (100.0)

134 (100.0)

NA

 Ampicillin/sulbactam

7 (24.1)

10 (7.5)

0.020*

 Piperacillin/tazobactam

2 (6.9)

0 (0.0)

0.031*

 Cefazolin

6 (20.7)

4 (3.0)

0.001*

 Cefotetan

2 (6.9)

0 (0.0)

0.031*

 Aztreonam

5 (17.2)

0 (0.0)

0.000*

 Ceftriaxone

5 (17.2)

1 (0.7)

0.000*

 Ceftazidime

3 (10.3)

0 (0.0)

0.005*

 Cefepime

4 (13.8)

0 (0.0)

0.001*

 Cefoperazone/sulbactam

0 (0.0)

0 (0.0)

NA

 Ertapenem

2 (6.9)

1 (0.7)

0.082

 Imipenem

3 (10.3)

2 (1.5)

0.040*

 Ciprofloxacin

5 (17.2)

0 (0.0)

0.000*

 Levofloxacin

4 (13.8)

0 (0.0)

0.001*

 Gentamicin

1 (3.4)

1 (0.7)

0.325

 Tobramycin

1 (3.4)

1 (0.7)

0.325

 Amikacin

0 (0.0)

1 (0.7)

1.000

 SMZ-TMP

4 (13.8)

2 (1.5)

0.008*

 Nitrofurantoin

13 (44.8)

21 (15.7)

0.000*

MDR strains

7 (24.1)

5 (3.7)

0.001*

CRKP strains

3 (10.3)

3 (2.2)

0.119

Multilocus sequence typing

 ST23

6 (20.7)

57 (42.5)

0.028*

 ST29

3 (10.3)

7 (5.2)

0.538

 ST65

2 (6.9)

12 (9.0)

1.000

 ST86

2 (6.9)

8 (6.0)

1.000

  1. Values are presented as No. (%) of isolates
  2. MDR Multi-drug resistant, CRKP Carbapenems-resistant K. pneumoniae, SMZ-TMP sulfamethoxazole and trimethoprim, NA not applicable, *P < 0.05