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Table 4 Comparing microbiological and molecular-epidemiological characteristics of K. pneumoniae strains between OHD patients and non-OHD patients

From: Clinical, microbiological, and molecular epidemiological characteristics of Klebsiella pneumoniae-induced pyogenic liver abscess in southeastern China

Characteristic Kp from OHD patients (n = 29) Kp from non-OHD patients (n = 134) P Value
Hypermucoviscosity 8 (27.6) 42 (31.3) 0.691
Capsular serotypes
 K1 11 (37.9) 55 (41.0) 0.757
 K2 5 (17.2) 26 (19.4) 0.788
 K5 1 (3.4) 7 (5.2) 1.000
 K20 1 (3.4) 2 (1.5) 0.447
 non-type 11 (37.9) 43 (32.1) 0.545
Virulence genes
aerobactin 22 (75.9) 117 (87.3) 0.197
rmpA 25 (86.2) 130 (97.0) 0.049*
iroN 4 (13.8) 36 (26.9) 0.138
kfuBC 17 (58.6) 99 (73.9) 0.100
wcaG 18 (62.1) 94 (70.1) 0.395
ybtA 23 (79.3) 97 (72.4) 0.443
magA 9 (31.0) 65 (48.5) 0.087
fimH 29 (100.0) 127 (94.8) 0.451
mrkD 29 (100.0) 134 (100.0) NA
uge 26 (89.7) 121 (90.3) 1.000
entB 24 (82.8) 120 (89.6) 0.475
ureA 27 (93.1) 118 (88.1) 0.646
Antimicrobial resistance
 Ampicillin 29 (100.0) 134 (100.0) NA
 Ampicillin/sulbactam 7 (24.1) 10 (7.5) 0.020*
 Piperacillin/tazobactam 2 (6.9) 0 (0.0) 0.031*
 Cefazolin 6 (20.7) 4 (3.0) 0.001*
 Cefotetan 2 (6.9) 0 (0.0) 0.031*
 Aztreonam 5 (17.2) 0 (0.0) 0.000*
 Ceftriaxone 5 (17.2) 1 (0.7) 0.000*
 Ceftazidime 3 (10.3) 0 (0.0) 0.005*
 Cefepime 4 (13.8) 0 (0.0) 0.001*
 Cefoperazone/sulbactam 0 (0.0) 0 (0.0) NA
 Ertapenem 2 (6.9) 1 (0.7) 0.082
 Imipenem 3 (10.3) 2 (1.5) 0.040*
 Ciprofloxacin 5 (17.2) 0 (0.0) 0.000*
 Levofloxacin 4 (13.8) 0 (0.0) 0.001*
 Gentamicin 1 (3.4) 1 (0.7) 0.325
 Tobramycin 1 (3.4) 1 (0.7) 0.325
 Amikacin 0 (0.0) 1 (0.7) 1.000
 SMZ-TMP 4 (13.8) 2 (1.5) 0.008*
 Nitrofurantoin 13 (44.8) 21 (15.7) 0.000*
MDR strains 7 (24.1) 5 (3.7) 0.001*
CRKP strains 3 (10.3) 3 (2.2) 0.119
Multilocus sequence typing
 ST23 6 (20.7) 57 (42.5) 0.028*
 ST29 3 (10.3) 7 (5.2) 0.538
 ST65 2 (6.9) 12 (9.0) 1.000
 ST86 2 (6.9) 8 (6.0) 1.000
  1. Values are presented as No. (%) of isolates
  2. MDR Multi-drug resistant, CRKP Carbapenems-resistant K. pneumoniae, SMZ-TMP sulfamethoxazole and trimethoprim, NA not applicable, *P < 0.05