Parameter | Group | Variable | Number (percentage) or Median (IQR) | p-value | |||
---|---|---|---|---|---|---|---|
Total PPS 2011 | With linezolid use PPS 2011 | Total PPS 2016 | With linezolid use PPS 2016 | ||||
Participating hospitals | Total | Â | 132 (100) | 49 (37.1) | 218 (100) | 95 (43.6) | 0.24 |
Number of hospital beds | Median (IQR) | 359 (182–607)* | 607 (410–822)** | 305 (186–548)* | 519 (310–728)** | 0.17*; 0.04** | |
Prevalence of patients with antimicrobial use | Median (IQR) | 25.1 (19.2–31.2)* | 29.5 (25.2–31.9)** | 26.2 (19.5–30.5)* | 28.7 (20.9–32.9)** | 0.67*; 0.59** | |
Hospital type | Primary care | 71 (100) | 13 (18.3) | 118 (100) | 29 (24.6) | 0.32 | |
Secondary care | 28 (100) | 18 (64.3) | 41 (100) | 28 (68.3) | 0.73 | ||
Tertiary care | 22 (100) | 15 (68.2) | 36 (100) | 30 (83.3) | 0.20 | ||
Specialized hospital | 10 (100) | 2 (20) | 23 (100) | 8 (34.8) | 0.44 | ||
Other/Unknown | 1 (100) | 1 (100) | 0 (0) | 0 (n.a.) | n.a. | ||
Hospital ownership | Public | n.a. | n.a. | 103 (100) | 57 (55.3) | n.a. | |
Private, not for profit | n.a. | n.a. | 63 (100) | 18 (28.6) | n.a. | ||
Private, for profit | n.a. | n.a. | 31 (100) | 11 (35.5) | n.a. | ||
Other/Unknown | n.a. | n.a. | 21 (100) | 9 (42.9) | n.a. | ||
Participating wards | Total |  | 2142 (100) | 98 (4.6) | 3182 (100) | 212 (6.7) | < 0.01 |
Number of ward beds | Median (IQR) | 25 (18–34)* | 20 (12–33)** | 26 (18–34)* | 24 (16–34)** | 0.01*; 0.08** | |
Prevalence of patients with antimicrobial use | Median (IQR) | 23.1 (10.0–39.3)* | 53.5 (33.3–72.9)** | 25.0 (11.5–40.0)* | 45.0 (33.3–63.6)** | 0.04*; 0.05** | |
Percentage of antimicrobials with reason in notes | Median (IQR) | 100 (50.0–100)* | 95.3 (60.0–100)** | 83.3 (44.4–100)* | 82.5 (33.8–100)** | < 0.01*; 0.01** | |
Percentage of linezolid among all antimicrobials | Median (IQR) | 0 (0–0)* | 9.5 (6.5–13.6)** | 0 (0–0)* | 9.1 (6.7–14.3)** | < 0.01*; 0.82** | |
Ward specialty | Medical (incl. Geriatrics, neurology) | 656 (100) | 25 (3.8) | 1034 (100) | 50 (4.8) | 0.32 | |
Surgical (incl. G/O, urology, ENT) | 711 (100) | 24 (3.4) | 952 (100) | 60 (6.3) | < 0.01 | ||
ICU | 201 (100) | 40 (20.0) | 346 (100) | 79 (22.8) | 0.43 | ||
Other/Not specified | 545 (100) | 9 (1.7) | 850 (100) | 23 (2.7) | 0.20 | ||
Region | West | 597 (100) | 16 (2.7) | 927 (100) | 54 (5.8) | < 0.01 | |
North | 349 (100) | 22 (6.3) | 312 (100) | 19 (6.1) | 0.91 | ||
Southwest | 404 (100) | 18 (4.5) | 813 (100) | 57 (7.0) | 0.08 | ||
Southeast | 250 (100) | 17 (6.8) | 420 (100) | 33 (7.9) | 0.62 | ||
East | 542 (100) | 25 (4.6) | 710 (100) | 49 (6.9) | 0.09 | ||
Included patients | Total |  | 41,539 (100) | 119 (0.3) | 64,412 (100) | 255 (0.4) | < 0.01 |
 | Patient specialty | Medical (incl. Geriatrics, neurology) | 16,276 (100) | 37 (0.2) | 27,704 (100) | 64 (0.2) | 0.95 |
 | Surgical (incl. G/O, urology, ENT) | 16,828 (100) | 39 (0.2) | 25,656 (100) | 119 (0.5) | < 0.01 | |
 | Intensive care | 1652 (100) | 40 (2.4) | 2674 (100) | 65 (2.4) | 0.99 | |
 | Other/Not specified | 6783 (100) | 3 (0.0) | 8378 (100) | 7 (0.1) | 0.37 |