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Table 2 Analysis of the three C. freundii strains isolated from fecal samples of leukemic patients

From: Genomic characterization of Citrobacter freundii strains coproducing OXA-48 and VIM-1 carbapenemase enzymes isolated in leukemic patient in Spain

Strain Genome size (bp) GC% ST MIC IPM (mg/L) Sensitive phenotype Resistance phenotype Genome composition/
size (bp)
ARGs Plasmid type Accession number
CF_154 5,444,819 51,5 169 ≥32 DOX, CST, FOF, NIT AMX, AMC, TZP, CEF, FEP, CRO, ERT, IPM, CIP, AMK, GEN, SXT. CF154_Chromosome/
5,143,118
blaCMY-81, blaOXA-48, blaTEM-150, aac3-IId, aph3-Ia, strA, strB, qnrB38, sulII. / CP038653
Plasmid_1 (p154_1)/
296,117
blaCTX-M-9, blaSHV-12, blaVIM-1, aac6-Ib-cr, aadA1-pm, aadA2, aadB, qnr-A1, catA1, sulI, dfr16. IncHI2 CP038654
Plasmid_2 (p154_2)/
5584
/ ColRNAI_1 CP038655
CF_565 5,471,065 51,5 169 ≥32 DOX, CST, FOF, NIT AMX, AMC, TZP, CEF, FEP, CRO, ERT, IPM, CIP, AMK, GEN, SXT. CF565_Chromosome/
5,207,876
blaCMY-81, blaOXA-48, blaTEM-150, aac3-IId, aph3-Ia, strA, strB, qnrB38, sulII. / CP038656
Plasmid_1 (p565_1)/
263,189
blaCTX-M-9, blaSHV-12, blaVIM-1, aac6-Ib-cr, aadA1-pm, aadA2, qnr-A1, catA1, sulI, dfr16. IncHI2 CP038657
CF_680 5,557,664 51,4 169 ≥32 DOX, CST, FOF, NIT AMX, AMC, TZP, CEF, FEP, CRO, ERT, IPM, CIP, AMK, GEN, SXT. CF680_Chromosome/
5,167,642
blaCMY-81, blaOXA-48, blaTEM-150, aac3-IId, aph3-Ia, strA, strB, qnrB38, sulII. / CP038658
Plasmid_1 (p680_1)/
385,971
blaCTX-M-9, blaOXA-9, blaSHV-12, blaTEM-150, blaVIM-1, aac6-Ib-cr, aadA1-pm, aadA2, aadB, qnr-A1, catA1, sulI, dfr16. IncHI2 CP038659
Plasmid_2 (p680_2)/
4051
/ ColRNAI_1 CP038660
  1. AMX Amoxicillin, AMC Amoxicillin/clavulanic acid, TZP Piperacillin + Tazobactam, CEF Cephalothin, FEP Cefepime, CRO Ceftriaxone, ERT Ertapenem, IPM Imipenem, CIP Ciprofloxacin, AMK Amikacin, GEN Gentamicin, DOX Doxycycline, CST; Colistin, FOF Fosfomycin, NIT Nitrofurantoin, SXT Sulfamethoxazole/trimethoprim, MIC Minimum Inhibitory Concentration, ARGs Antibiotic resistance genes, ST Sequence Type