Skip to main content

Table 1 Enterobacteriaceae (216 strains): results of GDM versus BMD as the reference method

From: Gradient diffusion antibiogram used directly on bronchial aspirates for a rapid diagnosis of ventilator-associated pneumonia

Antibiotic/method

Range

MIC 50

MIC 90

Susceptible (%)

Intermediate (%)

Resistant (%)

Kappa

Minor error (%)

Major and very major error (%)

Ceftazidime GDM

0.016- > 256

0.25

32

186 (86.1)

6 (2.8)

24 (11.1)

88.8

5 (2.3)

1 (0.5)

Ceftazidime BMD

< 0.06- > 32

0.25

32

185 (85.6)

5 (2.3)

26 (12.0)

Ceftolozane-tazobactam GDM

0.023- > 256

0.25

1.5

197 (91.2)

6 (2.8)

13 (6.0)

91.1

3 (1.4)

Ceftolozane-tazobactam BMD

< 0.06- > 32

0.25

1

199 (92.1)

5 (2.3)

12 (5.6)

Meropenem GDM

< 0.002- > 32

0.032

0.125

209 (96.8)

1 (0.5)

6 (2.8)

92.6

1 (0.5)

Meropenem BMD

< 0.06- > 32

< 0.06

1

209 (96.8)

7 (3.2)

Doripenem GDM

< 0.002- > 32

0.064

0.25

209 (96.8)

7 (3.2)

100

Doripenem BMD

< 0.06- > 32

< 0.06

0.5

209 (96.8)

7 (3.2)

  1. Range, MIC 50 and MIC 90 are given in mg/mL. GDM = gradient diffusion method, BMD = broth microdilution method