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Table 3 Effect of BMGlvA2 on intestinal morphology

From: Bombyx mori gloverin A2 alleviates enterotoxigenic Escherichia coli-induced inflammation and intestinal mucosa disruption

OrganizationIndicators-K88+K88P value
0.0 mg/kg4.0 mg/kg8.0 mg/kg0.0 mg/kg4.0 mg/kg8.0 mg/kgInteractionK88A
DuodenumVillus height (μm)420.14 ± 8.40a434.40 ± 14.82a417.23 ± 6.45a317.27 ± 6.89c394.78 ± 8.47ab343.29 ± 6.51b0.374< 0.00010.117
Crypt depth (μm)106.59 ± 2.35ab99.25 ± 2.28ab93.80 ± 1.89b115.07 ± 2.52a116.02 ± 4.49a81.47 ± 1.21c0.0860.4240.002
V/C3.10 ± 0.124.36 ± 0.094.50 ± 0.112.77 ± 0.043.57 ± 0.164.22 ± 0.070.1830.0010.002
JejunumVillus height (μm)211.80 ± 2.34ab231.49 ± 11.34a195.86 ± 4.34ab172.00 ± 5.217b179.65 ± 9.01b181.40 ± 3.99b0.5260.0140.565
Crypt depth (μm)91.64 ± 3.4990.52 ± 3.2075.90 ± 2.1479.59 ± 2.4977.33 ± 3.3774.45 ± 3.780.7030.1660.356
V/C2.39 ± 0.082.54 ± 0.082.63 ± 0.072.17 ± 0.032.31 ± 0.052.57 ± 0.100.8500.2500.217
IleumVillus height (μm)331.30 ± 18.31352.29 ± 14.47350.19 ± 6.04319.60 ± 6.21235.76 ± 13.57332.22 ± 14.500.9860.6710.779
Crypt depth (μm)91.40 ± 2.84b102.19 ± 3.72ab92.05 ± 0.99b123.23 ± 3.56a103.59 ± 5.33ab94.09 ± 2.38b0.1250.0900.241
V/C3.66 ± 0.20a3.46 ± 0.10ab3.81 ± 0.068a2.61 ± 0.07b3.38 ± 0.05ab3.51 ± 0.10ab0.2450.0630.245
  1. The data were expressed as mean ± SEM. Data with different superscript letters in a row indicated that the differences between different treatment groups were statistically significant (p < 0.05).V/C, the ratio of villus height to crypt depth