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Fig. 3 | Antimicrobial Resistance & Infection Control

Fig. 3

From: Cost-effectiveness analysis comparing ceftazidime/avibactam (CAZ-AVI) as empirical treatment comparing to ceftolozane/tazobactam and to meropenem for complicated intra-abdominal infection (cIAI)

Fig. 3

One-way deterministic sensitivity analysis for CAZ-AVI sequence vs. Ceftolozane/Tazobactam sequence, INB based on a willingness-to-pay threshold. Abbreviations: CAZ-AVI ceftazidime-avibactam, cIAI complicated intra-abdominal infection, EOT end-of-treatment, INB incremental net benefit, Prob probability, TOC test-of-cure, Tx treatment

. CAZ-AVI sequence: CAZ-AVI plus metronidazole, followed by colistin + tigecycline + high-dose meropenem.

Ceftolozane/tazobactam sequence: Ceftolozane/tazobactam plus metronidazole, followed by colistin + tigecycline + high-dose meropenem.

Note: A positive INB indicates the CAZ-AVI sequence is cost effective compared to the ceftolozane/ tazobactam sequence, and vice versa

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