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Table 1 Minimal inhibitory concentration for various antibiotics

From: Development of amoxicillin resistance in Escherichia coli after exposure to remnants of a non-related phagemid-containing E. coli: an exploratory study

IsolateMIC (mg/L)D68C AmpC & ESBL Detection set conclusion
E-test®Vitek®
amoxamclpitacfrxcfxtcftzcftxAmpC hyperproduction¥
pBS-E12> = 256> = 32> = 1288<=4<=1<=1No
EUR16<=2<=44<=4<=1<=1Yes
EUR1M1> = 256> = 32832> = 644<=1Yes
EUR1M2> = 256> = 321632> = 644<=1Yes
EUR1M3> = 256> = 32<=41616<=1<=1Yes
EUR1M4> = 256> = 3283232<=1<=1Yes
EUR1M5> = 256> = 328> = 64> = 6442Yes
EUR1M6256> = 32<=416> = 64<=1<=1Yes
EUR1M7> = 256> = 32832> = 644<=1Yes
EUR1M8> = 256> = 32<=41616<=1<=1Yes
EUR1M9256> = 32<=41616<=1<=1Yes
EUR1M10128> = 32<=41632<=1<=1Yes
EUR1M11128> = 32<=43216<=0.25<=0.25Yes
EUR1M12> = 256> = 3216321621Yes
EUR1M13> = 256> = 3216323221Yes
EUR1M14> = 256> = 321632161<=0.25Yes
EUR1M15196> = 32<=416160.5<=0.25Yes
EUR1M16196> = 32<=416160.5<=0.25Yes
EUR1M17256> = 32<=4323220.5Yes
EUR1M18> = 256> = 3216321621Yes
EUR1M19> = 256> = 32832162<=0.25Yes
EUR1M206416<=44<=40.5<=0.25Yes
EUR1M21> = 256> = 3216321641Yes
EUR1M22256> = 3216321641Yes
EUR1S1> = 256> = 32<=41632<=1<=1Yes
EUR1S2> = 256> = 32832> = 642<=1Yes
EUR1E1> = 256> = 32<=41632<=1<=1Yes
EUR21<=2<=42<=4<=1<=1No
EUR2M1> = 256> = 3288<=4<=1<=1Yes
  1. MICs were measured with ETEST® (bioMérieux, Marcy l’Etoile, France) (amoxicillin) or the VITEK 2® system (bioMérieux, Marcy l’Etoile, France). ¥Interpretation of D68C AmpC & ESBL Detection set according to manufacturers instruction. Zone diameters as measured in the D68C AmpC & ESBL Detection set are depicted in Supplementary table S3. amox: amoxicillin; amcl: amoxicillin-clavulanic acid; pita: piperacillin-tazobactam; cfrx: cefuroxime; cfxt: cefoxitin; cftz: ceftazidime; cftx: cefotaxime; mero: meropenem; imip: imipenem;M: amoxicillin-resistant mutant after exposure to remnants of the pBS-E12 and Sterillium®S: amoxicillin-resistant mutant after exposure to Sterillium® onlyE: amoxicillin-resistant mutant after exposure to E12 and Sterillium®