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Table 3 Pack-antibiotic regimen matching (optimal and adequate) in children weighing 15 kg (≈3.5 years of age)

From: The potential negative impact of antibiotic pack on antibiotic stewardship in primary care in Switzerland: a modelling study

Regimen

CAP

Otitis media

Tonsillopharyngitis

Sinusitis

Afebrile UTI

Substance

Single dose

N doses/day

Duration (in days)

WHO group: ACCESS

 Amoxicillin

25 mg/kg

2

7

  

1.05 (−1)

  

 Amoxicillin/clavulanate

25 mg/kg

2

3

    

0.80 (+ 1)

25 mg/kg

2

7

0.94

    

WHO group: WATCH

 Azithromycin

10 mg/kg

1

3

0.75 (+ 1)

0.75 (+ 1)

   

10 mg/kg

1

5

  

1.25 (−1)

  

WHO group: UNCLASSIFIED

 Cefuroxime

15 mg/kg

2

7

1.8 (+ 1)

    
  1. + 1 = optimized by adding a single dose; − 1 = optimized by subtracting a single dose
  2. CAP Community-acquired pneumonia, UTI Urinary tract infection
  3. The regimens are shown together with the number of dosing units required for that regimen. Antibiotics are listed alphabetically by WHO Access or Watch groups with unclassified antibiotics listed separately. Bold font indicates availability of an optimal pack for the listed antibiotic and regimen. Normal font indicates availability of an adequate pack for the listed antibiotic and regimen, meaning that matching could be achieved by adding or dropping a single dosing unit to the regimen or leftovers of < one single dosing unit. Listed regimens represent 14.6% (6/42 regimens) in this weight-example. All remaining regimens did not have matching optimal or adequate packs