Primary cohort (n = 331) | Validation cohort (n = 181) | |
---|---|---|
Clinical characteristics | ||
Age, years | 64.00 [52.00, 75.00] | 56.00 [43.00, 69.00] |
Female, No (%) | 125 (37.8) | 45 (24.9) |
Previous hospitalization, No (%) | 105 (31.7) | 40 (22.1) |
Diabetes, No (%) | 80 (24.2) | 34 (18.8) |
Chronic lung disease, No (%) | 32 (9.7) | 17 (9.4) |
Chronic renal disease, No (%) | 34 (10.3) | 5 (2.8) |
Liver cirrhosis, No (%) | 36 (10.9) | 6 (3.3) |
Bulbar palsy, No (%) | 8 (2.4) | 7 (3.9) |
Immunosuppressive status, No (%) | 41 (12.4) | 8 (4.4) |
MDRO, No (%) | 178 (53.8) | 97 (53.6) |
Organ function status | ||
Need of vasopressor agents, No (%) | 101 (30.5) | 55 (30.4) |
ALB, g/L | 29.50 [25.80, 32.65] | 29.00 [25.00, 34.00] |
TBil, umol/L | 17.30 [9.10, 33.10] | 18.40 [11.90, 25.00] |
PLT < 100 × 109/L, No (%) | 98 (29.9) | 33 (18.2) |
Cr, umol/L | 76.00 [55.00, 135.50] | 91.00 [65.00, 124.00] |
PaO2/FiO2, mmHg | 224.00 [153.50, 305.50] | 233.00 [175.00, 342.00] |
Indwelling catheter | ||
Tracheal intubation / incision, No (%) | 218 (65.9) | 133 (73.5) |
Indwelling urethral catheter, No (%) | 308 (93.1) | 169 (93.4) |
Indwelling central venous catheter, No (%) | 289 (87.3) | 81 (44.8) |
Laboratory indicators | ||
WBC, 109/L | 11.96 [7.69, 17.43] | 14.30 [11.70, 18.00] |
N% | 87.50 [81.40, 91.90] | 87.80 [83.90, 91.20] |
L% | 6.10 [3.50, 10.90] | 6.40 [4.50, 10.00] |
NLR | 14.26 [7.61, 25.49] | 13.61 [8.67, 19.80] |
PCT, ug/L | 1.86 [0.46, 16.93] | 0.38 [0.10, 2.46] |
CRP, mg/L | 67.90 [24.00, 90.00] | 98.10 [47.90, 169.50] |
Scores | ||
SOFA | 7.00 [4.00, 9.00] | 7.00 [5.00, 9.00] |
APACHEII | 14.00 [11.00, 18.50] | 20.00 [14.00, 25.00] |
Pitt | 2.00 [1.00, 4.50] | 4.00 [2.00, 7.00] |