Predicting the occurrence of multidrug-resistant organism colonization or infection in ICU patients: development and validation of a novel multivariate prediction model

Table 2 Logistic regression analysis of predictive factors for MDRO colonization or infection in ICU patients

	Univariate logistic regression analysis		Multivariate logistic regression analysis
	OR (95% CI)	P value	OR (95% CI)	P value
Age, years	1.004 (0.99–1.02)	0.526
Female	0.59 (0.38–0.92)	0.021	0.56 (0.35–0.89)	0.014
Previous hospitalization	1.22 (0.77–1.95)	0.403
Diabetes	1.40 (0.84–2.34)	0.201
Chronic lung disease	1.29 (0.62–2.76)	0.505
Chronic renal disease	1.44 (0.70–3.05)	0.326
Liver cirrhosis	0.66 (0.32–1.31)	0.237
Bulbar palsy	0.51 (0.10–2.10)	0.358
Immunosuppressive status	1.40 (0.72–2.78)	0.325
Need of vasopressor agents	1.04 (0.65–1.67)	0.870
ALB, g/L	1.03 (0.99–1.07)	0.158
TBil, umol/L	1.00 (0.99–1.003)	0.379
PLT < 100 × 10⁹/L	1.13 (0.70–1.83)	0.609
Cr, umol/L	1.00 (0.99–1.002)	0.912
PaO₂/FiO₂, mmHg	1.00 (0.99–1.002)	0.784
Tracheal intubation / incision	1.44 (0.91–2.29)	0.116
Indwelling urethral catheter	1.56 (0.67–3.76)	0.308
Indwelling central venous catheter	1.33 (0.69–2.55)	0.393
WBC, 10⁹/L	0.99 (0.97–1.02)	0.650
N%	0.99 (0.97–1.01)	0.442
L%	1.01 (0.98–1.05)	0.391
NLR	1.00 (0.99–1.01)	0.879
PCT, ug/L	1.00 (0.99–1.004)	0.430
CRP, 10 mg/L	1.05 (1.02–1.09)	0.004	1.06 (1.02–1.09)	0.002
SOFA	0.99 (0.93–1.05)	0.811
APACHEII	1.01 (0.97–1.05)	0.570
Pitt	1.13 (1.04–1.23)	0.003	1.13 (1.03–1.22)	0.006

MDRO multidrug-resistant organism; Alb albumin; TBil total bilirubin; PLT platelet; Cr creatinine; PaO₂/FiO₂ oxygenation index; WBC leucocyte count; N%, neutrophil percentage; L%, lymphocyte percentage; NLR neutrophil-to-lymphocyte ratio; PCT procalcitionin; CRP C- reactive protein; SOFA score Sequential Organ Failure Assessment score; APACHEII score Acute Physiology and Chronic Health Evaluation (APACHE) II score; Pitt score, Pitt bacteremia score

ISSN: 2047-2994