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Table 1 Baseline characteristics of patients with polymicrobial and monomicrobial Staphylococcus aureus bloodstream infection

From: Clinical characteristics and risk factors of polymicrobial Staphylococcus aureus bloodstream infections

CharacteristicsTotal
(n = 349)
Mono-SA-BSI
(n = 295)
Poly-SA-BSI
(n = 54)
p-value
Age, median years (IQR)59.00 (45.50,68.00)60.00 (48,68.00)51.00 (40.50,69.00)0.06
Male sex243 (69.6%)202 (68.5%)41 (75.9%)0.27
Co-morbidities
 Diabetes mellitus70 (20.1%)61 (20.7%)9 (16.7%)0.50
 Chronic kidney disease31 (8.9%)27 (9.2%)4 (7.4%)0.88
 Chronic liver disease16 (4.6%)14 (4.7%)2 (3.7%)1
 COPD or Severe asthma7 (2%)7 (2.4%)0 (0%)0.60
 Chronic cardiac insufficiency25 (7.2%)22 (7.5%)3 (5.6%)0.83
 Solid tumor57 (16.3%)48 (16.3%)9 (16.7%)0.94
 Trauma73 (20.9%)54 (18.3%)19 (35.2%)0.01
 Burn injury45 (12.9%)30 (10.2%)15 (27.8%)0.00
 Cerebrovascular accident39 (11.2%)28 (9.5%)11 (20.4%)0.02
CCI, median (IQR)3 (1,5)3 (2,5)2 (1,4.25)0.08
APACHE II score, median (IQR)12 (9,17)12 (8,16)15 (11,22)0.00
SOFA score, median (IQR)4 (2,6)3 (2,5)5 (2.75,10)0.01
Pitt Bacteremia Score, median (IQR)2 (1,4)1 (1,3)3.5 (2,6)0.00
Hospitalization ward
 ICU stay131 (37.5%)93 (31.5%)38 (70.4%)0.00
Previous treatment
 Parenteral nutrition122 (35%)91 (30.8%)31 (57.4%)0.00
 Mechanical ventilation112 (32.1%)76 (25.8%)36 (66.7%)0.00
 Antibiotic exposure302 (86.5%)251 (85.1%)51 (94.4%)0.06
 Surgery124 (35.5%)92 (31.2%)32 (59.3%)0.00
 Chemotherapy/radiation13 (3.7%)13 (4.4%)0 (0%)0.23
 Renal replacement therapy43 (12.3%)37 (12.5%)6 (11.1%)0.77
 Blood transfusion58 (16.6%)37 (12.5%)21 (38.9%)0.00
Invasive devices
 central line catheter167 (47.9%)132 (44.7%)35 (64.8%)0.01
 Indwelling urinary catheter175 (50.1%)132 (44.7%)43 (79.6%)0.00
 Intraperitoneal drainage33 (9.5%)26 (8.8%)7 (13%)0.34
Prior hospital stay, median days (IQR)8 (2,20)7 (1,19)13 (7,32.5)0.00
Nosocomial infection266 (76.2%)214 (72.5%)52 (96.3%)0.00
Neutropenia7 (2.0%)6 (2.0%)1 (1.9%)1
  1. Abbreviations: IQR Interquartile range, COPD Chronic obstructive pulmonary disorder, CCI Charlson Comorbidity Index, SOFA Sequential organ failure assessment, APACHE Acute physiology and chronic health evaluation, ICU Intensive care unit, SA-BSI Staphylococcus aureus bloodstream infection