Characteristics | Total (N = 335 patients) (%) | Group 1 (N = 44 patients) (%) | Group 2 (N = 282 patients) (%) | P (Group 1 vs. Group 2) | Group 3 (N = 9 patients) (%) |
---|---|---|---|---|---|
Age (years) | |||||
≤ 45 | 49 (14.6) | 4 (9.1) | 44 (15.6) | 0.23 | 1 (11.1) |
> 45 and < 75 | 132 (39.4) | 15 (34.1) | 115 (40.8) | 2 (22.2) | |
≥ 75 | 154 (46.0) | 25 (56.8) | 123 (43.6) | 6 (66.7) | |
Gender | Â | Â | Â | 0.29 | Â |
Female | 165 (49.3) | 25 (56.8) | 136 (48.2) | 4 (44.4) | |
Male | 170 (50.7) | 19 (43.2) | 146 (51.8) | 5 (55.6) | |
Cause of ICU admission | |||||
Respiratory problem | 117 (34.9) | 15 (34.1) | 97 (34.4) | 0.97 | 5 (55.6) |
Septic shock | 102 (30.4) | 16 (36.4) | 83 (29.4) | 0.35 | 3 (33.3) |
Post-surgical Observation | 38 (11.3) | 5 (11.4) | 33 (11.7) | 0.95 | 0 (0.0) |
Other causes | 78 (23.3) | 8 (18.2) | 69 (24.5) | 0.36 | 1 (11.1) |
Intra-abdominal surgery | 23 (6.9) | 4 (9.1) | 19 (6.8) | 0.53 | 0 (0.0) |
Pressure ulcer | 51 (15.2) | 9 (20.5) | 38 (13.5) | 0.22 | 4 (44.4) |
Wound | 17 (5.1) | 6 (13.6) | 10 (3.5) | 0.01 | 1 (11.1) |
Urinary catheter | 306 (91.3) | 44 (100.0) | 253 (89.7) | 0.02 | 9 (100.0) |
< 5 d | 176 (52.5) | 10 (22.7) | 163 (57.8) | < 0.0001 | 3 (33.3) |
≥ 5 d | 159 (47.5) | 34 (77.3) | 119 (42.2) | 6 (66.7) | |
Mechanical ventilation | 169 (50.4) | 36 (81.8) | 126 (44.7) | < 0.0001 | 7 (77.8) |
< 2 d | 204 (60.9) | 9 (20.5) | 190 (67.4) | 0.002 | 5 (55.6) |
≥ 2 d | 131 (39.1) | 35 (79.5) | 92 (32.6) | 4 (44.4) | |
BiPAP use at hospital | 83 (24.8) | 11 (25.0) | 70 (24.8) | 0.98 | 2 (22.2) |
BiPAP use at home | 25 (7.5) | 2 (4.5) | 23 (8.2) | 0.55 | 0 (0.0) |
Central line | 105 (31.3) | 19 (43.2) | 82 (29.1) | 0.06 | 4 (44.4) |
Kemal catheter | 33 (9.9) | 6 (13.6) | 27 (9.6) | 0.42 | 0 (0.0) |
Hemodialysis in ICU | 44 (13.1) | 5 (11.4) | 39 (13.8) | 0.66 | 0 (0.0) |
Use of vasopressors | 173 (51.6) | 27 (61.4) | 141 (50.0) | 0.16 | 5 (55.6) |
APACHE II score | |||||
< 20 | 220 (65.7) | 27 (61.4) | 189 (67.0) | 0.46 | 4 (44.4) |
≥ 20 | 115 (34.3) | 17 (38.6) | 93 (33.3) | 5 (55.6) | |
Between 20 and 29 | 86 (25.7) | 15 (34.1) | 68 (73.1) | 0.35 | 3 (33.3) |
≥ 30 | 29 (8.7) | 2 (4.5) | 25 (26.9) | 2 (22.2) | |
CCI score | |||||
0 | 38 (11.3) | 3 (6.8) | 34 (12.1) | 0.047 | 1 (11.1) |
1–2 | 31 (9.3) | 4 (9.1) | 26 (9.2) | 1 (11.1) | |
3–4 | 75 (22.4) | 12 (27.3) | 61 (21.6) | 2 (22.2) | |
5–6 | 97 (29.0) | 19 (43.2) | 76 (27.0) | 2 (22.2) | |
7–8 | 62 (18.5) | 6 (13.6) | 55 (19.5) | 1 (11.1) | |
> 8 | 32 (9.6) | 0 (0.0) | 30 (10.6) | 2 (22.2) | |
< 4 | 91 (27.2) | 12 (27.3) | 76 (27.0) | 0.96 | 3 (33.3) |
≥ 4 | 244 (72.8) | 32 (72.7) | 206 (73.0) | 6 (66.7) | |
XDR-AB contact pressure | 147 (43.9) | 33 (75.0) | 113 (40.1) | < 0.0001 | 1 (11.1) |
< 3 d | 252 (75.2) | 14 (31.8) | 230 (81.6) | < 0.0001 | 8 (88.9) |
≥ 3 d | 83 (24.8) | 30 (68.2) | 52 (18.4) | 1 (11.1) | |
Blood Transfusion | 98 (29.3) | 11 (25.0) | 82 (29.1) | 0.58 | 5 (55.6) |
CAR use | 195 (58.2) | 31 (70.5) | 157 (55.7) | 0.06 | 7 (77.8) |
< 4 d | 208 (62.1) | 19 (43.2) | 185 (65.6) | 0.004 | 4 (44.4) |
≥ 4 d | 127 (37.9) | 25 (56.8) | 97 (34.4) | 5 (55.6) | |
< 7 d | 246 (73.4) | 25 (56.8) | 216 (76.6) | 0.005 | 5 (55.6) |
≥ 7 d | 89 (26.6) | 19 (43.2) | 66 (23.4) | 4 (44.4) | |
TZP use | 119 (35.5) | 23 (52.3) | 93 (33.0) | 0.01 | 3 (33.3) |
< 4 d | 275 (82.1) | 34 (77.3) | 234 (83.0) | 0.36 | 7 (77.8) |
≥ 4 d | 60 (17.9) | 10 (22.7) | 48 (17.0) | 2 (22.2) | |
CAR or TZP use | 259 (77.3) | 43 (97.7) | 207 (73.4) | < 0.0001 | 9 (100.0) |
< 4 d | 164 (49.0) | 12 (27.3) | 149 (52.8) | 0.002 | 3 (33.3) |
≥ 4 d | 171 (51.0) | 32 (72.7) | 133 (47.2) | 6 (66.7) | |
LOS in the ICU | |||||
< 4 days | 175 (52.2) | 7 (15.9) | 164 (58.2) | < 0.0001 | 4 (44.4) |
≥ days | 160 (47.8) | 37 (84.1) | 118 (41.8) | 5 (55.6) | |
Number of patients who stayed in the ICU during each numerical week after ETDa | |||||
Week 1 | 54 (16.1) | 6 (13.6) | 44 (15.6) | 0.74 | 4 (44.4) |
Week 2 | 35 (10.4) | 5 (11.4) | 27 (9.6) | 0.78 | 3 (33.3) |
Week 3 | 37 (11.0) | 5 (11.4) | 32 (11.3) | 1.00 | 0 (0.0) |
Week 4 | 35 (10.4) | 5 (11.4) | 29 (10.3) | 0.79 | 1 (11.1) |
Week 5 | 38 (11.3) | 6 (13.6) | 31 (11.0) | 0.61 | 1 (11.1) |
Week 6 | 31 (9.3) | 8 (18.2) | 21 (7.4) | 0.04 | 2 (22.2) |
Week 7 | 30 (9.0) | 7 (15.9) | 21 (7.4) | 0.08 | 2 (22.2) |
Week 8 | 38 (11.3) | 6 (13.6) | 31 (11.0) | 0.61 | 1 (11.1) |
Week 9 | 36 (10.7) | 8 (18.2) | 26 (9.2) | 0.11 | 2 (22.1) |
Week 10 | 19 (5.7) | 5 (11.4) | 14 (5.0) | 0.15 | 0 (0.0) |
Week 11 | 25 (7.5) | 7 (15.9) | 17 (6.0) | 0.03 | 1 (11.1) |
Week 12 | 26 (7.8) | 8 (18.2) | 17 (6.0) | 0.01 | 1 (11.1) |
Week 13 | 22 (6.6) | 7 (15.9) | 14 (5.0) | 0.01 | 1 (11.1) |
Week 14 | 20 (6.0) | 10 (22.7) | 10 (3.5) | < 0.0001 | 0 (0.0) |
Week 15 | 17 (5.1) | 8 (18.2) | 9 (3.2) | 0.001 | 0 (0.0) |
Week 16 | 18 (5.4) | 6 (13.6) | 12 (4.3) | 0.02 | 0 (0.0) |