High rate of extended-spectrum beta-lactamase-producing gram-negative infections and associated mortality in Ethiopia: a systematic review and meta-analysis

Table 2 Species distribution of the pooled proportion of ESBL-producing Gram-negative bacteria

Gram-negative bacteria	No. of studies	No. of isolates	No. of ESBL-positive isolates	ESBL Proportion [95% CI]	I² (p-value)
Klebsiella spp.	10	400	263	0.66 [.61; .70]	< 0.001
Enterobacter spp.	6	53	33	0.61 [.47; .74]	< 0.001
Salmonella spp.	5	186	90	0.48 [.33; .63]	< 0.001
E. coli	10	815	383	0.47 [.44; .50]	< 0.001
Citrobacter spp.	5	47	22	0.47[.33;,63]	0.001
Providencia spp.	3	16	7	0.44 [.20; .70]	0.011
Proteus spp.	6	53	15	0.28 [.16; .42]	0.053
Pseudomonas aeruginosa	2	23	4	0.17 [.05; .39]	0.386
Acinetobacter spp.	3	32	3	0.09	–
Others^a	5	24	5	0.09 [.02;.25]	0.142
Total		1649	825	0.25 [.09; .49]	< 0.0001

^aOthers: Alcaligenes faecalis (1 ESBL of 3 isolates), Morganella morganii (3 ESBL of 12 isolates); Stenotrophomonas maltophilia (1 ESBL of 4 isolates), Escherichia hermanii (1 ESBL of 1 isolates)

ISSN: 2047-2994