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Table 3 Expression of efflux pump genes in evolved, resistant P. aeruginosa, selected by ciprofloxacina

From: Development of in vitro resistance to fluoroquinolones in Pseudomonas aeruginosa

Passage

mexA

mexC

mexE

mexX

0. (0MIC)

1.0000

1.0000

1.0000

1.0000

1. (1/2MIC)

1.3075

9.0280

11.9735

2.3705

2. (1MIC)

0.6615

9.9210

10.1515

1.3515

3. (2MIC)

1.0715

144.4805

6.5980

2.1285

4. (4MIC)

0.8040

11.4565

6.3370

1.4735

5. (8MIC)

0.6125

86.9080

5.0330

1.7635

6. (16MIC)

0.8320

195.6205

8.3245

3.5535

7. (32MIC)

0.6140

132.7665

7.0495

3.5345

8. (64MIC)

0.7175

112.6305

10.0960

4.5755

  1. aRelative expression levels represent the median of the six lineages