A seven-year surveillance study of the epidemiology, antifungal susceptibility, risk factors and mortality of candidaemia among paediatric and adult inpatients in a tertiary teaching hospital in China

Table 5 Factors associated with 30-days mortality by multivariate analysis^a

Variable	All patients			Adult patients
Variable	Odds ratio	95% confidence interval	P-value	Odds ratio	95% confidence interval	P-value
Median age	1.02	0.973–1.065	0.444	1.03	0.957–1.109	0.427
Length of hospital stay(days)	0.88	0.809–0.964	0.005	0.89	0.802–0.99	0.032
Respiratory dysfunction	13.78	2.254–84.198	0.005	22.57	2.014–252.84	0.011
Pulmonary infection	0.68	0.125–3.693	0.655	0.98	0.142–6.743	0.982
Cardiovascular disease	0.65	0.088–4.787	0.672	3.36	0.269–41.933	0.347
Chronic/acute renal failure	2.50	0.464–13.425	0.287	1.19	0.191–7.392	0.854
Other invasive catheters	0.04	0.002–0.695	0.028	0.04	0.001–1.233	0.066
Mechanical ventilation	4.59	0.554–37.999	0.158	12.56	0.981–160.793	0.052
Septic shock	99.97	11.997–832.995	< 0.001	89.72	10.161–792.184	< 0.001
Diabetes mellitus^b	0.12	0.013–1.038	0.054	–	–	–
C. Albicans^b	–	–	–	3.16	0.391–25.505	0.281
Concomitant bacterial infection^b	–	–	–	4.97	0.42–58.742	0.204
Hematologic (nonmalignant)^b	–	–	–	0.27	0.018–4.057	0.346
Total parenteral nutrition^b	–	–	–	0.06	0.004–1.06	0.055
ICU/PICU/NICU^b	–	–	–	0.31	0.029–3.259	0.328

ICU intensive care unit; PICU pediatric intensive care unit, NICU neonatal intensive care unit
^aBecause the total number of pediatric patients(35 patients) and deaths (3 patients) were very small, multivariable logistic regression analysis was not performed in pediatric patients
^b Biologically plausible variables with a value of P > 0.1 according to the univariate analyses were not included in the multiple logistic regression model

ISSN: 2047-2994