Table 6 Protective factor and predictors of 30-day mortality in others studies
Authors | Country or region | study period | study design | samples | No of samples | Protective factor | Predictors of 30-day mortality | Reference |
|---|---|---|---|---|---|---|---|---|
Ma et al | China | 2009–2011 | Retrospective, observational, single-center study | Candidemia((130 adults and 3 children < 15 years patients) | 133 |  | Presence of CVC | 37 |
Cortes et al | Colombia | 2008–2009 | Retrospective, observational, multicenter study (seven tertiary-care hospitals) | Candidemia(9 days to 87 years patients) | 131 | Fluconazole therapy | Age, the presence of shock at the time of Candida detection | 40 |
Wang et al | China | 2008–2010 | Retrospective, multicentre study (4 tertiary general hospitals) | Candidemia(> 16 years patients) | 147 | Antifungal therapy administered before microbiological documentation | Absence of antifungal therapies, receipt of mechanical ventilation and APACHE II score ≥ 20 | 41 |
Tedeschi et al | Italy | 2012–2013 | Retrospective, observational, multicenter cohort study(39 hospitals) | Candidemia (adult patients) | 232 | Central-venous-catheter removal and adequate and timely(within 72 h of drawing blood cultures) therapy | Chronic-obstructive-pulmonary-disease and isolation of C. tropicalis | 42 |
Li et al | China | 2010–2014 | Retrospective, observational, single-center study | Candidemia(> 18 years patients) | 190 | Proven catheter-related candidemia | Severe sepsis or septic shock | 35 |
Gonzalez-Lara et al | Mexico | 2008–2014 | Retrospective, laboratory-based survey study(two tertiary-care centers hospitals) | Candidemia(all patients) | 149 | Early CVC withdrawal andempirical antifungal therapy | Severe sepsis and previous diagnosis of cirrhosis | 43 |
Jia et al | China | 2011–2016 | Retrospective, observational, multicenter study (3 hospitals) | Candidemia(15–90 years patients) | 198 |  | ICU admission, catheter-relatedcandidemia, ascites, septic shock and concomitant bacterial infection | 18 |
Ortega-Loubon et al | Spain | 2007–2016 | Retrospective, observational, single-cente study | Candidemia(> 18 years patients) | 296 |  | Prolonged mechanical ventilation, age and low lymphocyte count | 23 |
Kato et al | Japan | 2011–2016 | Retrospective, observational, multicenter study (5 hospitals) | Candidemia(all patients) | 289 | Follow-up blood culture,empiric treatment with fluconazole | Age > 65 years and SOFA score ≥ 6 | 5 |
Ala-Houhala et al | Finland | 2007–2016 | Retrospective, observational study (2 hospitals) | Candidemia(> 18 years patients) | 374 |  | Severity of underlying illnesses, ICU stay at the onset of candidemia and age > 65 years | 4 |
Medeiros et al | Brazil | 2011–2016 | Retrospective, single-center, observational cohort study | Nosocomial candidemia | 68 |  | Older age, severe sepsis and hypotension | 25 |
Santolaya et al | Chile | 2013–2017 | Prospective, observational multicenter, laboratory-based survey study(26 tertiary care hospitals) | Candidemia(all patients) | 780 |  | Mechanical ventilation and previous use of corticosteroids | 17 |
Alkharashi et al | Saudi Arabia | 2013–2018 | Retrospective, observational, single-cente study | Candidemia(> 18 years patients) | 324 |  | Use of broad-spectrum antibiotics and use of central venous catheters | 24 |
Xiao et al | China | 2011–2017 | Retrospective, observational, single-cente study | Candidemia(26–91 years patients) | 82 |  | GCS score, P/F ratio, MAP | 36 |
This study | China | 2013–2019 | Retrospective, observational, single-cente, cohort study | Candidemia(0–5 years and > 16 years patients) | 201 | Length of hospital stay(days) | Respiratory dysfunction and Septic shock | This study |