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Table 1 Microbiological and molecular characteristics of the CMY-producing E. coli isolates

From: Detection of CMY-type beta-lactamases in Escherichia coli isolates from paediatric patients in a tertiary care hospital in Mexico

Key MIC (μg/mL) CAZ
CLOX
CAZ
BOR
AmpC type ESBL test Other enzymes PFGE ST131-O25b clone Phylogroup MLST CC
CRO CAZ FEP FOX IMP MEM ETP
Ec 24 > 32 ≥ 16 ≥ 16 128 ≤ 1 ≤ 1 1 + CMY-2 + CTX-M-15 NT D ST405 405
Ec 35 > 32 ≥ 16 ≥ 16 > 128 ≤ 1 ≤ 1 ≤ 0.5 + CMY-2 + CTX-M-79 NR F ST457 ND
Ec 41 > 32 ≥ 16 ≥ 16 64 ≤ 1 ≤ 1 ≤ 0.5 CMY-2 + TEM-1, CTX-M-15 NR F ST648 648
Ec 55 > 32 ≥ 16 ≥ 16 > 128 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-2 + CTX-M-15 NR A ST10 10
Ec 65 > 32 ≥ 16 ≥ 16 128 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-2 + CTX-M-15 NR B2 ST12 12
Ec 109 > 32 ≥ 16 ≥ 16 16 ≤ 1 ≤ 1 ≤ 0.5 CMY-2 + CTX-M-15 NR A ST10 10
Ec 223 > 32 8 ≥ 16 128 ≤ 1 ≤ 1 ≤ 0.5 + CMY-2 + CTX-M-15 NR + B2 ST131 ND
Ec 278 > 32 ≥ 16 ≤ 2 128 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-2 Absent NR A ST168 168
Ec 394 > 32 ≥ 16 ≥ 16 > 128 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-42 TEM-190 NR A ST1284 10
Ec 445 > 32 ≥ 16 ≥ 16 128 ≥ 4 ≥ 4 ≥ 2 CMY-2 + CTX-M-15, OXA-48 NR A ST10 10
Ec 480 > 32 ≥ 16 ≥ 16 > 128 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-42 Absent NT A ST361 ND
Ec 481 > 32 ≥ 16 ≥ 16 128 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-42 + TEM-190 NR C ST23 23
Ec 599 16 ≥ 16 ≤ 2 64 ≤ 1 ≤ 1 ≤ 0.5 + CMY-2 TEM-1 NR A ST101 101
Ec 668 > 32 ≥ 16 ≥ 16 128 ≤ 1 ≤ 1 1 + + CMY-42 + CTX-M-15 NR A ST10 10
Ec 678 8 8 ≤ 2 128 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-2 Absent NR E ST350 350
Ec 686 > 32 ≥ 16 ≥ 16 128 ≤ 1 ≤ 1 1 + + CMY-2 + CTX-M-15 NR D ST69 69
Ec 689 8 8 ≤ 2 64 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-2 TEM-1 NR A ND ND
Ec 714 > 32 ≥ 16 ≥ 16 64 ≤ 1 ≤ 1 ≤ 0.5 + + CMY-2 + CTX-M-15 NR Clade I ND ND
  1. In bold are the high-risk clone
  2. MIC minimum inhibitory concentration, CRO ceftriaxone, CAZ ceftazidime, FEP cefepime, FOX cefoxitin, IMP imipenem, MEM meropenem, ETP ertapenem, CLOX cloxacillin, BOR boronic acid, ESBL extended-spectrum beta-lactamases, PFGE pulsed-field gel electrophoresis, MLST multilocus sequence typing, CC clonal complex, NT non-typeable, ND not determined, NR not related