Table 5 Mutations in the quinolone resistance determining region (QRDR) of gyrA, gyrB, parC and parE in 21 strains of Staphylococcus epidermidis
Mutation type | No. of isolates | Mutation | |||
|---|---|---|---|---|---|
gyrA | gyrB | parC | parE | ||
1 | 7 | Ser84Phe | – | Ser80Tyr | – |
2 | 4 | Ser84Phe | – | Ser80Phe | – |
3 | 3 | Ser84Phe | – | Ser80Phe + Asp84Val | – |
4 | 1 | Ser84Tyr | – | Ser80Ile | – |
5 | 1 | Ser84Tyr | – | Ser80Ile | Lys402Arg + Asn404Ile |
6 | 1 | Ser84Phe | – | Ser80Phe + Asp84Val | Lys403Thr + Asn404Asp |
7 | 1 | Ser84Phe | – | Ser80Phe + Asp84Val | Lys402Arg + Lys403Arg |
8 | 1 | Ser84Tyr + Glu88Lys | – | Ser80Phe + Asp84Tyr | – |
9 | 1 | Ser84Phe | – | Ser80Phe | Asp434Val |
10 | 1 | – | – | – | – |