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Table 2 Values for the quality indicators at baseline and across the post-intervention period for both groups

From: Impact of a multifaceted intervention to improve antibiotic prescribing: a pragmatic cluster-randomised controlled trial

ESAC Quality
Indicators [25]
Group Period
Baseline (median 48 monthsb) Post-intervention (median 19 monthsb)
1. DID of antibiotics for systemic use Intervention 15.9 (15.8–16.0) 13.8 (13.7–14.0)
Control 14.9 (14.8–15.0) 13.5 (13.4–13.6)
2. DID of penicillins Intervention 9.1 (9.1–9.2) 7.9 (7.8–8.0)
Control 8.0 (7.9–8.0) 7.3 (7.3–7.4)
3. DID of cephalosporins Intervention 1.9 (1.9–1.9) 1.5 (1.5–1.5)
Control 1.8 (1.8–1.8) 1.5 (1.5–1.5)
4. DID of macrolides, lincosamides and streptogramins Intervention 1.6 (1.6–1.6) 1.4 (1.4–1.4)
Control 1.7 (1.7–1.8) 1.6 (1.5–1.6)
5. DID of quinolones Intervention 2.1 (2.1–2.1) 1.9 (1.8–1.9)
Control 2.1 (2.1–2.1) 1.9 (1.9–2.0)
6. PCT of beta-lactamase sensitive penicillinsa Intervention 0.6 (0.6–0.7) 0.6 (0.5–0.6)
Control 0.4 (0.4–0.4) 0.4 (0.3–0.4)
7. PCT of combinations of penicillins with beta-lactamase inhibitors a Intervention 42.1 (42.0–42.3) 40.0 (39.8–40.3)
Control 39.0 (38.9–39.2) 38.2 (38.0–38.4)
8. PCT of 3rd- and 4th-generation cephalosporins a Intervention 4.0 (3.9–4.0) 2.8 (2.7–2.9)
Control 4.2 (4.8–4.3) 3.3 (3.2–3.4)
9. PCT of quinolones Intervention 13.3 (13.2–13.4) 13.4 (13.2–13.5)
Control 14.3 (14.2–14.4) 14.3 (14.1–14.4)
10. Ratio of consumption of broad- to narrow-spectrum penicillins, cephalosporins and macrolides Intervention 68.9 (67.6–70.1) 49.3 (47.5–51.0)
Control 59.9 (58.8–60.9) 45.0 (43.6–46.5)
  1. Abbreviations. PCT Percentage, DID Defined daily doses per 1000 inhabitants per day, ESAC European Surveillance of Antimicrobial Consumption
  2. a Percentage of total consumption of antibiotics for systemic use in DID
  3. b The interventions were implemented from December 2011 to July 2012