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Table 1 Number of studies in qualitative synthesis and meta-analysis for each burden of disease measure by AMR type

From: Evaluation of the health and healthcare system burden due to antimicrobial-resistant Escherichia coli infections in humans: a systematic review and meta-analysis

Burden of disease measure (outcome)

Number of studies in the qualitative synthesis

(number of studies included in the meta-analysis)

Third-generation cephalosporin resistance

Quinolone resistance

Multidrug resistance

30-day mortality

23 (23)

9 (8)

4 (4)

All-cause mortality

51 (51)

17 (16)

5 (5)

Bacterial-attributable mortality

3 (3)

0 (0)

0 (0)

Treatment failure

15 (n/a)

7 (n/a)

2 (n/a)

Total LOS

13 (5)

4 (3)

1 (0)

Post-infection LOS

7 (2)

0 (0)

0 (0)

Hospital costs

4 (n/a)

0 (n/a)

2 (n/a)

  1. LOS, length of hospital stay; n/a, not applicable, meta-analysis not planned as per protocol; AMR, antimicrobial resistance