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Table 3 Phenotypic resistance of E. coli isolates by study cycle

From: Caretaker knowledge, attitudes, and practices (KAP) and carriage of extended-spectrum beta-lactamase-producing E. coli (ESBL-EC) in children in Quito, Ecuador

Class

Antibiotic

Cycle 1

No. of isolates (%)a

n = 277

Cycle 2

No. of isolates (%)

n = 239

Total No. of Isolates among both cycles

(n = 516)

Cephalosporin/β-lactamase inhibitor

Cefazolin

277 (100%)

238 (99.6)

515 (99.8)

Ceftazidime

72 (26.0)

58 (24.3)

130 (25.2)

Cefepime

121 (43.7)

106 (44.4)

227 (44.0)

Cefotaxime

256 (92.4)

227 (95.0)

483 (93.6)

Amoxicillin/clavulanic acid

63 (22.7)

43 (18.0)

106 (20.4)

Penicillin

Ampicillin

275 (99.3)

238 (99.6)

513 (99.4)

Aminoglycoside

Gentamycin

47 (17.0)

47 (19.7)

94 (18.2)

Carbapenem

Imipenem

2 (0.7)

1 (0.4)

3 (0.6)

Fluroquinolone

Ciprofloxacin

137 (49.5)

118 (49.4)

255 (49.4)

Tetracycline

Tetracycline

201 (72.6)

187 (78.2)

388 (75.2)

Folate pathway inhibitors

Trimethoprim-Sulfamethoxazole

185 (66.8)

157 (65.7)

342 (66.3)

ESBL-producing

52 (18.8)

43 (18.0)

95 (18.4)

Multidrug-resistant to three or more classesb

231 (83.4)

217 (90.8)

448 (86.4)

  1. Antibiotic susceptibility testing was performed on bacteria strains that had previously grown on MacConkey agar with ceftriaxone. Percentages represent percent of isolates tested
  2. aStrains tested were determined to be the same isolate if they came from the same fecal sample and had the same resistance pattern
  3. bMultidrug resistant E. coli were determined from isolates resistant to ceftriaxone