2007–2008 N = 113 | 2009–2010 N = 268 | 2011–2012 N = 212 | 2013–2014 N = 232 | 2015–2016 N = 180 | Total N = 1005 | Change* | ||
---|---|---|---|---|---|---|---|---|
Absolute | Relative | |||||||
Acinetobacter | ||||||||
Aminoglycosides | 10 (71.4%) | 16 (45.7%) | 8 (44.4%) | 7 (46.7%) | 6 (50.0%) | 47 (50.0%) | −21.4% | −30.0% |
B-lactam | 10 (76.9%) | 14 (58.3%) | 10 (90.9%) | 6 (54.5%) | 6 (75.0%) | 46 (68.7%) | −1.9% | −2.5% |
Carbapenems | 10 (71.4%) | 17 (63.0%) | 13 (81.3%) | 10 (66.7%) | 6 (60.0%) | 56 (68.3%) | −11.4% | − 16.0% |
Cephalosporins | 11 (84.6%) | 22 (66.7%) | 14 (82.4%) | 13 (100.0%) | 7 (70.0%) | 67 (77.9%) | −14.6% | −17.3% |
Fluoroquinolones | 10 (71.4%) | 20 (58.8%) | 14 (77.8%) | 10 (66.7%) | 7 (63.6%) | 61 (66.3%) | −7.8% | −10.9% |
MDR3 | 10 (71.4%) | 20 (58.8%) | 14 (77.8%) | 9 (60.0%) | 6 (54.5%) | 59 (64.1%) | −16.9% | −23.6% |
MDR4 | 10 (71.4%) | 18 (52.9%) | 11 (61.1%) | 7 (46.7%) | 6 (54.5%) | 52 (56.5%) | −16.9% | −23.6% |
MDR5 | 8 (57.1%) | 7 (20.6%) | 5 (27.8%) | 4 (26.7%) | 6 (54.5%) | 30 (32.6%) | −2.6% | −4.5% |
Pseudomonas | ||||||||
Aminoglycosides | 6 (18.2%) | 10 (14.9%) | 6 (11.8%) | 9 (13.8%) | 3 (6.3%) | 34 (12.9%) | −11.9% | −65.6% |
B-lactam | 9 (30.0%) | 15 (25.0%) | 2 (5.4%) | 19 (30.6%) | 8 (18.2%) | 53 (22.7%) | −11.8% | −39.4% |
Carbapenems | 5 (15.2%) | 11 (42.3%) | 8 (40.0%) | 9 (50.0%) | 9 (52.9%) | 42 (36.8%) | 37.8% | 249.4% |
Cephalosporins* | 12 (35.3%) | 24 (36.4%) | 6 (12.8%) | 9 (15.0%) | 4 (9.3%) | 55 (22.0%) | −26.0% | −73.6% |
Fluoroquinolones | 2 (5.9%) | 11 (16.4%) | 7 (13.7%) | 9 (14.8%) | 5 (10.9%) | 34 (13.1%) | 5.0% | 84.8% |
MDR3 | 4 (11.8%) | 11 (16.2%) | 6 (11.8%) | 7 (10.9%) | 4 (8.5%) | 32 (12.1%) | −3.3% | −27.7% |
MDR4 | 2 (5.9%) | 8 (11.8%) | 4 (7.8%) | 6 (9.4%) | 2 (4.3%) | 22 (8.3%) | −1.6% | −27.7% |
MDR5 | 1 (2.9%) | 4 (5.9%) | 1 (2.0%) | 5 (7.8%) | 2 (4.3%) | 13 (4.9%) | 1.3% | 44.7% |
Klebsiella | ||||||||
Aminoglycosides | 7 (28.0%) | 24 (46.2%) | 20 (32.8%) | 16 (24.6%) | 15 (32.6%) | 82 (32.9%) | 4.6% | 16.5% |
B-lactam | 3 (17.6%) | 14 (50.0%) | 10 (37.0%) | 14 (31.8%) | 15 (40.5%) | 56 (36.6%) | 22.9% | 129.7% |
Carbapenems | 0 (0.0%) | 4 (13.3%) | 3 (11.5%) | 4 (14.3%) | 6 (33.3%) | 17 (13.9%) | 33.3% | – |
Cephalosporins | 6 (27.3%) | 19 (63.3%) | 14 (48.3%) | 17 (34.7%) | 16 (43.2%) | 72 (43.1%) | 16.0% | 58.6% |
Fluoroquinolones | 4 (18.2%) | 21 (46.7%) | 19 (33.9%) | 12 (18.5%) | 11 (24.4%) | 67 (28.8%) | 6.3% | 34.4% |
MDR3 | 2 (8.0%) | 16 (35.6%) | 11 (22.4%) | 10 (17.2%) | 11 (23.9%) | 50 (22.4%) | 15.9% | 198.9% |
MDR4 | 2 (8.0%) | 5 (11.1%) | 3 (6.1%) | 7 (12.1%) | 7 (15.2%) | 24 (10.8%) | 7.2% | 90.2% |
MDR5 | 0 (0.0%) | 1 (2.2%) | 0 (0.0%) | 2 (3.4%) | 5 (10.9%) | 8 (3.6%) | 10.9% | – |
Enterobacte | ||||||||
Aminoglycosides | 0 (0.0%) | 7 (14.0%) | 2 (6.7%) | 5 (16.7%) | 2 (7.1%) | 16 (10.5%) | 7.1% | – |
B-lactam | 2 (50.0%) | 5 (22.7%) | 3 (37.5%) | 1 (50.0%) | 2 (50.0%) | 13 (32.5%) | 0.0% | 0.0% |
Carbapenems | 0 (0.0%) | 1 (6.7%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (1.6%) | 0.0% | – |
Cephalosporins | 2 (50.0%) | 10 (52.6%) | 3 (50.0%) | 2 (33.3%) | 5 (55.6%) | 22 (50.0%) | 5.6% | 11.1% |
Fluoroquinolones | 0 (0.0%) | 4 (8.7%) | 2 (6.7%) | 0 (0.0%) | 3 (10.7%) | 9 (6.1%) | 10.7% | – |
MDR3 | 0 (0.0%) | 1 (3.6%) | 2 (16.7%) | 0 (0.0%) | 2 (13.3%) | 5 (6.2%) | 13.3% | – |
MDR4 | 0 (0.0%) | 0 (0.0%) | 1 (8.3%) | 0 (0.0%) | 0 (0.0%) | 1 (1.2%) | 0.0% | – |
MDR5 | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0.0% | – |
Escherichia coli | ||||||||
Aminoglycosides | 5 (31.3%) | 14 (40.0%) | 14 (35.0%) | 12 (31.6%) | 9 (34.6%) | 54 (34.8%) | 3.4% | 10.8% |
B-lactam | 5 (45.5%) | 6 (28.6%) | 5 (35.7%) | 6 (23.1%) | 9 (60.0%) | 31 (35.6%) | 14.5% | 32.0% |
Carbapenems | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (4.8%) | 3 (15.8%) | 4 (4.4%) | 15.8% | – |
Cephalosporins | 10 (66.7%) | 10 (45.5%) | 14 (56.0%) | 17 (47.2%) | 14 (53.8%) | 65 (52.4%) | −12.8% | −19.2% |
Fluoroquinolones | 7 (46.7%) | 13 (38.2%) | 18 (51.4%) | 18 (46.2%) | 9 (36.0%) | 65 (43.9%) | −10.7% | −22.9% |
MDR3 | 4 (26.7%) | 9 (34.6%) | 6 (18.8%) | 7 (18.9%) | 5 (19.2%) | 31 (22.8%) | −7.4% | −27.9% |
MDR4 | 3 (20.0%) | 1 (3.8%) | 2 (6.3%) | 3 (8.1%) | 4 (15.4%) | 13 (9.6%) | −4.6% | −23.1% |
MDR5 | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 1 (2.7%) | 0 (0.0%) | 1 (0.7%) | 0.0% | – |
Others* | ||||||||
Aminoglycosides | 5 (50.0%) | 7 (25.9%) | 1 (11.1%) | 4 (23.5%) | 2 (16.7%) | 19 (25.3%) | −33.3% | −66.7% |
B-lactam | 3 (42.9%) | 2 (25.0%) | 1 (33.3%) | 2 (28.6%) | 2 (28.6%) | 10 (31.3%) | −14.3% | −33.3% |
Carbapenems | 3 (33.3%) | 9 (56.3%) | 2 (50.0%) | 2 (40.0%) | 7 (70.0%) | 23 (52.3%) | 36.7% | 110.0% |
Cephalosporins | 5 (55.6%) | 10 (52.6%) | 2 (33.3%) | 2 (22.2%) | 4 (40.0%) | 23 (43.4%) | −15.6% | −28.0% |
Fluoroquinolones | 2 (25.0%) | 7 (25.0%) | 1 (11.1%) | 3 (16.7%) | 1 (9.1%) | 14 (18.9%) | −15.9% | −63.6% |
MDR3 | 4 (40.0%) | 5 (29.4%) | 1 (16.7%) | 1 (9.1%) | 2 (22.2%) | 13 (24.5%) | −17.8% | −44.4% |
MDR4 | 2 (20.0%) | 2 (11.8%) | 0 (0.0%) | 1 (9.1%) | 1 (11.1%) | 6 (11.3%) | −8.9% | −44.4% |
MDR5 | 2 (20.0%) | 2 (11.8%) | 0 (0.0%) | 0 (0.0%) | 1 (11.1%) | 5 (9.4%) | −8.9% | −44.4% |
Overall | ||||||||
Aminoglycosides | 32 (31.7%) | 75 (31.5%) | 48 (25.4%) | 50 (23.9%) | 34 (21.7%) | 239 (26.7%) | −10.0% | −31.6% |
B-lactam | 31 (41.9%) | 54 (36.7%) | 30 (33.0%) | 45 (31.5%) | 39 (36.8%) | 199 (35.5%) | −5.1% | −12.2% |
Carbapenems | 18 (19.4%) | 39 (32.2%) | 26 (28.3%) | 25 (26.3%) | 29 (35.4%) | 137 (28.4%) | 16.0% | 82.7% |
Cephalosporins | 48 (54.5%) | 93 (54.1%) | 52 (42.6%) | 60 (37.0%) | 51 (40.2%) | 304 (45.3%) | −14.4% | −26.4% |
Fluoroquinolones | 25 (26.0%) | 73 (32.3%) | 59 (32.8%) | 48 (23.3%) | 33 (21.7%) | 238 (27.7%) | −4.3% | −16.6% |
MDR3 | 23 (23.0%) | 61 (31.4%) | 39 (25.5%) | 33 (18.4%) | 28 (20.1%) | 184 (24.1%) | −2.9% | −12.4% |
MDR4 | 19 (19.0%) | 34 (17.5%) | 21 (13.7%) | 23 (12.8%) | 19 (13.7%) | 116 (15.2%) | −5.3% | −28.1% |
MDR5 | 11 (11.0%) | 12 (6.2%) | 6 (3.9%) | 12 (6.7%) | 12 (8.6%) | 53 (6.9%) | −2.4% | − 21.5% |