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Table 3 Risk factors for death within 30 days after Enterococcus faecium bacteraemia (Cox regression; n = 177)

From: Does vancomycin resistance increase mortality in Enterococcus faecium bacteraemia after orthotopic liver transplantation? A retrospective study

  Univariate Multivariate
Variables Dead
n = 21
Alive
n = 156
HR 95% CI p HR 95% CI p
Definitive infectious focus elimination
 Yes 6 (28.6) 40 (25.6) 0.85 0.33–2.20 0.745 0.50 0.19–1.37 0.181
 No 15 (71.4) 116 (74.4)       
Start of adequate AB Therapy within < 48 h post-BSI onset
 Yes 14 (66.7) 90 (57.7) 1.47 0.59–3.64 0.407 1.03 0.39–2.74 0.952
 No 7 (33.3) 66 (42.3)       
Mean SOFANon-GCS (day-7 until day-1 before BSI onset) 12.8 ± 3.8 6.8 ± 4.7 1.30 1.16–1.46 < 0.001 1.32 1.14–1.53 < 0.001
ICU stay between day-7 and BSI onset [days] 7.6 ± 1.2 5.0 ± 3.5 1.47 1.08–2.00 0.014 1.01 0.71–1-44 0.966
Bacteraemia
 VRE 6 (15.4) 33 (84.6) 1.49 0.58–3.84 0.409 1.80 0.64–5.03 0.264
 VSE 15 (10.9) 123 (89.1)       
  1. Data are presented as n (%) or mean ± standard deviation.
  2. Abbreviations: HR hazards ratio, CI confidence interval, AB antibiotic therapy, BSI bloodstream infection, SOFA sequential organ failure assessment, GCS Glasgow coma scale, VRE vancomycin-resistant Enterococcus faecium, VSE vancomycin-susceptible Enterococcus faecium