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Table 4 Experimental results for particle size and drug entrapment efficiency of various formulations

From: Enhanced bactericidal effect of ceftriaxone drug encapsulated in nanostructured lipid carrier against gram-negative Escherichia coli bacteria: drug formulation, optimization, and cell culture study

Sample

Solid lipid

Liquid lipid

Surfactant of the internal water phase

Surfactant of the external water phase

Particle size (nm)

Drug loading(%)

S1

GMS

Oleic acid

Soy lecithin

Tween 80

86.09

83%

S2

GMS

Oleic acid

Span 80

PVA

112.41

80%

S3

GMS

Sesame oil

Soy lecithin

Tween 80

101.95

75%

S4

GMS

Sesame oil

Span 80

PVA

127.41

73%

S5

Stearic acid

Oleic acid

Soy lecithin

Tween 80

202.74

72%

S6

Stearic acid

Oleic acid

Span 80

PVA

260.52

69%

S7

Stearic acid

Sesame oil

Soy lecithin

Tween 80

306.75

60%

S8

Stearic acid

Sesame oil

Span 80

PVA

369.67

58%