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Table 3 Clinical manifestations of the 24 patients colonized with CRE

From: Different screening frequencies of carbapenem-resistant Enterobacteriaceae in patients undergoing hematopoietic stem cell transplantation: which one is better?

PtAge /SexDisease/HSCTCRE IsolateWhich times screening turned positiveFebrile episodes in carriersTime from colonization to fever (day)Time from fever to the use of tigecycline (hour)ANC at fever (×109/L)Symptoms at feverCRP (mg/L) /PCT (ug/L)30 days status
Single screening
1a36/FALL/HaploE.coli/Yes−3> 720Abdominal pain, diarrhoea216.8/1.0Dead
256/FMM/AutoE. coli1Yes7< 240Chills, tremble95.1/4.1Alive
332/mALL/MUDK.pneumoniae1Yes5< 240No48.9/normalAlive
Continuous screening
436/MAML/HaploK.pneumoniae5No/////Alive
515/MAML/HaploE. coli2Yes9< 240Chills, tremble73.0/normalAlive
627/MALL/HaploE. coli3Yes8< 240No52.2/normalAlive
748/MAML/HaploE.coli2Yes4< 240Perianal inflammation112.3/ normalAlive
845/MAML/HaploK.pneumoniae4No/////Alive
940/MAL/HaploK.pneumoniae1No/////Alive
1038/MT-LBL/HaploE. coli3Yes11< 240.5No43.2/normalAlive
1116/FALL/HaploE. coli1Yes17< 240No54.2/normalAlive
1218/MALL/MUDE.coli2Yes9< 240Chills, tremble64.5/normalAlive
1325/MALL/HaploE.coli2Yes8< 240No61.2/normalAlive
1434/FAML/HaploK.pneumoniae3No/////Alive
1544/MMM/AutoE.coli4No/////Alive
1650/MAML/SibK.pneumoniae1Yes15< 240sore throat70.4/normalAlive
1718/MALL/HaploK.pneumoniae5No/////Alive
1851/MALL/HaploE.coli5No/////Alive
1922/MALL/HaploK.pneumoniae4No/////Alive
2022/FAML/HaploK.pneumoniae3Yes1> 480Chills, tremble65.2/0.6Alive
2126/MALL/MUDK.pneumoniae1Yes13< 240No73.4/normalAlive
2227/MALL/HaploK.pneumoniae6No/////Alive
2321/MAML/HaploK.pneumoniae2Yes12< 240Perianal
inflammation
307/ normalAlive
2462/MAML/HaploK.pneumoniae6Yes2< 240No141.7/normalAlive
  1. Abbreviations: AML Acute myeloid leukemia, ALL Acute lymphatic leukemia, AL Acute leukemia, Auto Autologous HSCT, CRP C-reactive protein (normal value: 0-8 mg/L)E.coli Escherichia coli, Haplo HLA-Haploidentical allogeneic HSCT, K.pneumoniae Klebsiella pneumoniae, MM Multiple myeloma, MUD Matched-unrelated donor allogeneic HSCT, PCT Procalcitonin (normal value:< 0.5μg/L), Sib HLA-sibling allogeneic HSCT, T-LBL T-lymphoblastic lymphoma
  2. aThe patient 1:single screening was negative for the patient, but subsequent screening indicated positive 3 days after the onset of fever and the patient died of septic shock
  3. 1.Four patients (2,12,20,23) were combined with polymyxin because of persistent fever after 48 h of tigecycline treatment, one of them (patient 20) developed CRE BSIs later