Skip to main content

Table 2 Resistance rates (%) of major gram-positive bacteria of PBM patients in China, 2016–2018

From: Prevalence and antimicrobial resistance patterns of bacteria isolated from cerebrospinal fluid among children with bacterial meningitis in China from 2016 to 2018: a multicenter retrospective study

Antimicrobial agent Sep
A/B (%)
Sho
A/B (%)
Sha
A/B (%)
Spn
A/B (%)
Efa
A/B (%)
GBS
A/B (%)
SA
A/B (%)
Oxacillin 132/165 (80.0) 51/67 (76.1) 31/36 (86.1) 9/31 (29.0)
Penicillin G 143/159 (89.9) 58/66 (87.9) 28/33 (84.8) 92/116 (82.8) 90/92 (97.8) 1/58 (1.7) 1/29 (96.6)
Amoxicillin 26/103 (25.2)
Ampicillin 106/111 (95.5) 1/27 (3.7)
Cefotaxime 48/117 (41.0)
Ceftriaxone 17/34 (50.0)
Erythromycin 134/160 (83.8) 50/70 (71.4) 35/36 (97.2) 112/116 (96.6) 107/109 (98.2) 28/31 (90.3) 22/31 (71.0)
Clindamycin 60/65 (92.3) 45/49 (91.8) 9/25 (36.0)
Gentamicin 44/163 (27.0) 14/69 (20.3) 23/36 (63.9) 2/31 (6.5)
Ciprofloxacin 46/165 (27.9) 15/69 (21.7) 30/36 (83.3) 102/110 (92.7) 1/32 (3.2)
Moxifloxacin 29/94 (30.9) 13/55 (23.6) 10/17 (58.8) 0/78 (0) 0/19 (0)
Levofloxacin 30/98 (30.6) 8/58 (13.8) 10/19 (52.6) 0/118 (0) 58/65 (89.2) 28/59 (47.5) 2/21 (9.5)
Rifampin 27/163 (16.6) 8/66 (12.1) 12/35 (34.3) 1/31 (3.2)
Nitrofurantoin 66/105 (62.9) 0/30 (0)
Co-trimoxazole 57/164 (34.8) 17/67 (25.4) 30/36 (83.3) 101/119 (84.9) 8/31 (25.8)
Tetracycline 45/165 (27.3) 19/68 (27.9) 14/37 (37.8) 107/117 (91.5) 83/111 (74.8) 33/48 (68.8) 7/32 (21.9)
Vancomycin 0/164 (0) 0/71 (0) 0/37 (0) 0/120 (0) 1/111 (0.9) 0/50 (0) 0/31 (0)
Linezolid 0/192 (0) 0/82 (0) 0/41 (0) 0/94 (0) 5/114 (4.4) 0/56 (0) 0/38 (0)
Tigecycline 0/63 (0)
  1. PBM, pediatric bacterial meningitis; Sep, Staphylococcus epidermidis; Sho, Staphylococcus hominis; Sha, Staphylococcus haemolyticus; Spn, Streptococcus pneumoniae; Efa, Enterococcus faecium; GBS, group B Streptococcus; SA, Staphylococcus aureus
  2. A/B (%), number resistant/number tested (percentage resistant)
  3. A dash (–) indicates that antibiotics were not tested against the isolated pathogens