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Table 4 Empiric antimicrobial use and prescribing quality indicators from 2015 to 2020

From: Effects of coronavirus disease 2019 (COVID-19) pandemic on antimicrobial prevalence and prescribing in a tertiary hospital in Singapore

Year 2015 2017 2018 2019 2020 P
No. of anti-microbials 768 755 839 821 780
Empiric treatment 608 (79%) 538 (71%) 660 (79%) 577 (70%) 532 (68%)
Reasons in notes 697 (91%) 733 (97%) 746 (89%) 772 (94%) 755 (97%) < 0.01
Stop/review date 404 (53%) 323 (43%) 450 (54%) 458 (56%) 476 (61%) < 0.01
Guideline complianta 340/479 (71%) 291/375 (78%) 286/403 (71%) 235/377 (62%) 248/344 (73%) 0.08
No guideline available 96/589 (16%) 66/480 (14%) 138/560 (25%) 108/507 (21%) 110/463 (24%)
Surgical prophylaxis > 24 h 20/36 (56%) 20/34 (59%) 11/26 (42%) 18/26 (69%) 15/27 (52%) 0.76
  1. aThe number of antimicrobial prescriptions for which guidelines were available was used as the denominator to calculate percentages. Only includes empiric and surgical prophylaxis use. P = test for trends in proportions